10 Best Wrinkle Facial Serum of December 2025

• 1-fluid ounce pump bottle of RoC Retinol Correxion Deep Wrinkle Anti-Aging Facial Serum designed to complement skin's renewal process and reduce the appearance of fine lines and wrinkles
• Anti-Aging Ingredients - Facial serum features a unique formula with retinol, magnesium, zinc, and copper to help bring newer skin to the surface and reduce the signs of aging
• For All Skin Types - Light, silky wrinkle serum glides on easily and absorbs quickly, leaving skin feeling smooth and velvety, and is non-comedogenic
• Clinical Results - Smooths fine lines and makes skin look more radiant and firm in just 4 weeks, and has been clinically proven to visibly reduce the appearance of fine lines and deep wrinkles in 12 weeks
• Every Day Wrinkle Treatment - Designed for daily use, smooth this retinol serum all over face and neck after skin has been cleansed and dried, allowing wrinkle treatment to be absorbed quickly

RoC

• A dermatologist-grade Vitamin C serum that combines 15% Pure Vitamin C and Hyaluronic Acid for brighter and firmer skin in just 10 days.
• LiftActiv Vitamin C Serum is pure yet potent, with a minimalist formula of only 11 ingredients that is paraben-free and fragrance-free.
• Creates a visibly brighter and firmer complexion, smooths the appearance of skin texture, and reduces the look of fine lines in just 10 days.
• Pure and potent antioxidant formula helps address uneven skin tone and helps fight against signs of skin aging.
• Suitable for all skin types

Vichy

• Experience America's #1 Most Awarded Retinol* now available in a gentle daily facial cleanser, for skin care that removes dirt, oil, & long-wear makeup. Removes oil, dirt, even long-wear makeup trapped on the surface & enriches skin with Retinol & Niacinamide anti-aging benefits, leaving skin looking healthy & revitalized throughout the day.
• PROVEN RESULTS: Immediately after use, 100% of women said this was the most effective cleanser they have ever tried.100% of women saw instantly more radiant, smoother-looking skin; After just 2 weeks, 97% of women had an improvement in skin firmness & a visible reduction in fine lines & wrinkles, even deep ones.
• ANTI-AGING FORMULAS: Whether you're looking for a solution for deep wrinkles, fine lines, dark circles, crow's feet, uneven skin tone or dry skin, we have an anti-aging formula that's right for you, and suitable for sensitive skin.
• SCIENCE & BEAUTY: We produce a wide array of skin care products & treatments including daily moisturizers with SPF, hyaluronic and niacinamide acids, facial cleansers, vitamin C serums, retinol skin tone & wrinkle regimens & creams for under eyes, neck firming, decollete & much more.
• Fragrance Free; Soap-Free; Sulfate Free; Paraben-Free; Non-Comedogenic Face Wash; Tested on the face and eye area; Ophthalmologist Tested; Dermatologist Tested *Based on a 3rd party study using publicly available data sources from publications and media sources hosting beauty awards since 2010

RoC

• ANTI-WRINKLE SERUM TREATMENT: Made with pure RoC Retinol and RoC's exclusive mineral complex for additional hydration & enhanced Retinol efficacy, this serum works to complement skin’s renewal process and bring fresher, revitalized-looking skin to the surface. The longer you use it - the more dramatic age-defying results you will see. Gentle enough for daily use by men and women.
• PROVEN RESULTS: With daily use, this serum is clinically proven to help deliver smoother, more radiant skin in 4 weeks & diminish the look of photodamage in 8 weeks. Deep wrinkles, even those that are deep-set appear visibly reduced. Non-greasy. Non-comedogenic. Dermatologist-tested. Paraben-Free.
• ANTI-AGING FORMULAS: Whether you're looking for a solution for deep wrinkles, fine lines, dark circles, crow's feet, uneven skin tone or dry skin, we have an anti-aging formula that's right for you.
• SCIENCE & BEAUTY: We produce a wide array of skin care products & treatments including daily moisturizers with SPF, hyaluronic and niacinamide acids, facial cleansers, vitamin C serums, retinol skin tone & wrinkle regimens & creams for under eyes, neck firming, decollete & much more.
• SKIN CARE INNOVATION: Our products are recognized by beauty industry leaders & dermatologists for their best-in-class effectiveness. We continue to research & innovate new formulas for healthier skin.

RoC

• Plant Based Formulation - Free of synthetic color additives, fragrance, and stabilizers, dynamic active botanicals like Aloe Vera, Witchhazel, Botanical Hyaluronic Acid, Witch Hazel and organic Jojoba oil combine in a silky smooth serum that can be used day or night.
• Anti-Aging Vitamin C Serum For Face - As you grow older, the skin loses its vitality, leaving it dull, dry and dehydrated. Vitamin C Serum contains Hyaluronic Acid and botanical blend that helps fight against wrinkles and spots. Including Vitamin C Serum in your daily skin care, helps add moisture on face and skin, nourishes the skin and helps to retain its natural glow.
• Advanced Antioxidant Serum - An indispensable nutrient for collagen production, vitamin C blends with Botanical Hyaluronic Acid and Vitamin E, designed to target the most common signs of aging, including firmness, fine lines, wrinkles, dark spots & sun spots.
• Stimulate Collagen Formation - Vitamin C is responsible for collagen production. Boosting your skin and body with Vitamin C Serum will enhance the natural formation of collagen that is the number one component for connecting tissues for skin health. No oily residue left behind. Absorbs quickly without a heavy, greasy or sticky feel.

ELBBUB

• DUAL-ACTION WRINKLE FILLER: See visible results instantly & over time with this dual-action intensive wrinkle filler formulated with retinol & hydrating hyaluronic acid. It immediately begins to fill creases and re-plump skin. With daily use, it continues to improve the look of skin so that even deep wrinkles appear diminished in as little as 4 weeks. Gentle enough for daily use by men and women.
• PROVEN RESULTS: Instantly, creases begin to fill to reduce appearance of fine lines - re-plumped skin appears softer & smoother. This clinically proven anti-wrinkle formula with glycerin & antioxidants helps diminish the look of crow's feet & deep wrinkles in 4 weeks. Non-comedogenic. Dermatologist-tested.
• ANTI-AGING FORMULAS: Whether you're looking for a solution for deep wrinkles, fine lines, dark circles, crow's feet, uneven skin tone or dry skin, we have an anti-aging formula that's right for you.
• SCIENCE & BEAUTY: We produce a wide array of skin care products & treatments including daily moisturizers with SPF, hyaluronic and niacinamide acids, facial cleansers, vitamin C serums, retinol skin tone & wrinkle regimens & creams for under eyes, neck firming, decollete & much more.
• SKIN CARE INNOVATION: Our products are recognized by beauty industry leaders & dermatologists for their best-in-class effectiveness. We continue to research & innovate new formulas for healthier skin.

RoC

• Packaging May Vary. 1.0-fluid ounces of Neutrogena Rapid Wrinkle Repair Retinol Antiwrinkle Oil Serum helps minimize the look of the signs of aging by reducing appearance of stubborn fine lines and wrinkles, with visible results in just 1 week
• This product is non-sealed
• The perfect addition to a daily skincare routine, this anti-wrinkle retinol serum is fast absorbing and is clinically proven to reduce the appearance of stubborn and deep wrinkles, and intensely nourish and renew the look of skin
• Known to reduce visible signs of skin aging, pure 0.3% retinol is scientifically proven superior to commonly used retinyl esters. The face oil is free of parabens, mineral oil and dyes and comes from the no.1 retinol brand used most by dermatologists

Neutrogena

• Efficacy: Rich in natural hyaluronic acid, deeply moisturize the skin, smooth fine lines and shrink pores
• Sensitive Skin Gospel: Pure natural ingredients, mildly moisturizing and non-irritating
• How to store : Stored in dry and cool place, please avoid the direct sunlight and deviate from any high temperature, stay away from children and avoid any accidents
• Ingredients: Water, Butanediol, Sodium Hyaluronate, AGARICUS-BISPORUS Extract, Palmityl pentapeptide-4, Palmityl Oligopeptide, Carnosine, Aloe Vera Extract, Panthenol, Nicotinamide, PAEONIAALBIFLORA Root Extract, Carbomer, Triethanolamine
• Made with 100 percent Natural ingredients, no preservative added. Provide 24-hour messages/Email after-sales service
• Scent name: Original Flavor
• Unit count type: Ounce
• Safety warning: The main ingredients of the product are water and hyaluronic acid. Please drop it on the back of your hand to test. It can be used normally if there is no allergic reaction in 30 minutes. Do not drip into your eyes. If it gets into your eyes, please rinse your eyes with clean water in time. If you still feel unwell, please consult a doctor immediately.
• Ingredients: Water, Hyaluronate Sodium, Butanediol, AGARICUS-BISPORUS Extract, Palmityl pentapeptide-4, Palmityl Oligopeptide, Carnosine, Aloe Vera Extract, Panthenol, Nicotinamide, PAEONIAALBIFLORA Root Extract, Carbomer, Triethanolamine

YOUXI

• Packaging May Vary. 1-fluid ounce tube of Neutrogena Rapid Wrinkle Repair Retinol Anti-Wrinkle Face Serum. In a clinical trial, 100% of women experienced noticeable results in just one week of use
• Lightweight, silky retinol serum to help smooth the look of fine lines and texture, brighten and even skin tone, and fades the look of deep, stubborn wrinkles, including crow's feet
• With retinol, a dermatologist-proven form of vitamin A and powerful ingredient that fights fine lines, dullness, wrinkles and dark spots
• Also contains hyaluronic acid, which adds plumping moisture to help hydrate and rejuvenate the look of skin. Plus the serum is free of mineral oil and dyes
• The perfect addition to a daily at-home anti-age skincare routine, this anti-wrinkle retinol serum is proven to work quickly with visible results in just one week and is the #1 retinol brand used most by dermatologists
• Accelerated retinol-SA
• Smoothes fine lines and texture
• Fades the look of stubborn wrinkles

Neutrogena

• Our best-selling hyaluronic acid serum is formulated with Pure Hyaluronic Acid and 15 Mineral-Rich Vichy Volcanic Water to strengthen & repair your skin barrier.
• This daily hydrating and plumping booster has been clinically tested by 175 dermatologists on 1600 women worldwide.
• Safe and effective for all skin types, in a minimalist, fragrance free formula with only 11 ingredients. Alcohol free. Silicone Free.
• Lightweight, fast-absorbing translucent booster
• Accepted by the National Eczema Association

Vichy