10 Best Peptide Complex Serum of December 2025

List of Top Rated Peptide Complex Serum from thousands of customer reviews & feedback.

Updated On Dec 2025

2,302 Reviews Studied

By Customer Ratings

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Collagen Peptide Complex Serum - Tighten, Firm & Smooth - Advanced Natural & Organic Anti-Aging Facial Formulation by Fo... Read Review

  • RESTORE THE NATURAL BEAUTY OF YOUR SKIN: Do you think it's too late to look amazing at your age? Reveal your skin's natural glow. Upgrade to Foxbrim Naturals' NEW advanced *9* plant peptide and amino acid formulation. Look great. Feel even better.
  • NINE PLANT-BASED PEPTIDES: Stimulate your skin's natural collagen production helping to reduce wrinkles and fine lines while improving skin volume, smoothness and thickness. Your skin will crave the all-natural peptides in an amino acid blend.
  • FEEL THE HYDRATION: Perfect with microneedling. For fast absorption, Hyaluronic Acid, Gotu Kola and Jojoba Oil deeply penetrate skin, helping to heal, and moisturize. Perfect around eyes for smooth, supple skin. Perfect for dry or sensitive skin.
  • ETHICALLY SOURCED AND PRODUCED: Vegan. Bottled in small batches. Never tested on animals. Proudly made in the USA.
  • THE FOXBRIM NATURALS EXPERIENCE: We care deeply about your experience and will not be satisfied unless you are. If you are unhappy with your purchase, let us know. We will take care of you.

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Collagen Peptide Complex Face Serum Anti Aging with Matrixyl 3000 and Hyaluronic Acid, Ultimate Skin Repair, Brightening... Read Review

  • SOFTEN WRINKLES & DIMINISH FINE LINES- Peptides are the best at promoting collagen growth. 
  • FIRMER, PLUMPER, GLOWING SKIN- Matrixyl 3000, Trylagen, and Hyaluronic Acid work together. 
  • DERMATOLOGIST TESTED & GREAT FOR SENSITIVE SKIN- We're also cruelty free & fragrance free. 
  • NON-GREASY, ABSORBS FAST- Oil free and in an aloe base for easy absorption into the skin. 
  • EXTENDED GUARANTEE FROM MANUFACTURER-If you're not happy for any reason, contact us for a full refund with 90 days. 

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Collagen Peptide Complex Serum-Anti Aging Serum With Niacinamide, Vegan Collagen, Retinol, Hyaluronic Acid & Vitamin C-P... Read Review

  • Anti Aging Serum For Face: The soluble collagen in our anti wrinkle serum helps plump up the skin cells in epidermis, acting as a wrinkle filler to give skin a smoother look. Our potent peptide complex serum has Matrixyl 3000 which has shown to reduce the density and volume of deep wrinkles by boosting the production of collagen.
  • Experience Skin Renewal With Niacinamide, Hyaluronic Acid, Retinol For Face & Vitamin C Skin Serum: Our Collagen Peptide Serum is fortified with powerhouse anti aging ingredients. They help in bringing radiance, replenishing skin by reducing free radical damage, while improving water retention & skin barrier function.
  • Hydrating Serum With Moisturizing & Healing Formula: What makes our Collagen Face Serum stand out further is the addition of non comedogenic (non pore clogging) facial oils & botanical extracts, rich in vitamins & antioxidant properties to help skin fight further against free radicals, any inflammation and keeping it hydrated.
  • Suitable For All Skin Types With Quantity to Last Long: We understand that skincare is a commitment that needs consistency and patience to get results. That is why, we have packed 4oz of our serum so you do not run out without experiencing the difference. Best part is our 4x bigger bottle comes within the same price range as other similar serums! Suitable for oily skin, normal, dry and combination. Love it! Pass on the gift of beautiful skin to your loved ones!
  • Satisfaction Guaranteed: Our peptide serum for face is proudly Made In The USA. It is formulated with Vegan Ingredients without any parabens or unsafe ingredients. Our anti aging serum is Cruelty Free and not tested on animals. While it is gentle and suitable for all skin types, we do understand that every skin is unique. If for any reason, you are not satisfied, feel free to contact us and we will be happy to make it right for you.

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TruSkin Peptide Serum For Face with Collagen Boosting Peptides, Amino Acids, Green Tea, Aloe and Vitamins B5 & E, 1 fl o... Read Review

  • POTENT SKIN NUTRITION – Infused with powerful Peptides, Silk Amino Acids and antioxidant-rich Green Tea, this nourishing pro collagen Peptide Serum nurtures tone, texture and tautness with potent daily nutrition.
  • BARRIER BOOSTING HYDRATION – Our fragrance-free Peptides serum for face is soaked with a nutrient-dense blend of Vitamins B5 & E, Aloe, and Botanical Hyaluronic Acid for a triple-shot of anti aging, barrier-boosting hydration.
  • POWER OF PEPTIDES – Peptides are short chains of amino acids that build skin’s vital proteins. Our Peptide Complex serum contains a collagen-friendly Peptide-Amino Acid Complex for robust, resilient skin.
  • CRUELTY FREE & MANUFACTURED IN THE USA – All TruSkin products are manufactured and bottled in the USA for guaranteed freshness—and they’re always Leaping Bunny-certified cruelty free.
  • EXTENDED MANUFACTURER GUARANTEE – Love it or your money back! If for any reason you decide this product isn't a good fit for your skin, we offer a 90-day money-back refund.

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Peptide Complex Facial Serum with Matrixyl 3000 & Argireline for Face/Neck - Anti Aging & Deep Wrinkles, Heals and Repai... Read Review

  • OUR PEPTIDES SERUM BOASTS NIACINAMIDE AND HYALURONIC ACID to smooth away wrinkles and improve elasticity for a stunningly youthful glow. In addition to being an anti-aging skincare must-have ingredient and skin plumper Peptides are touted as natural healing agents! Our proprietary peptide complex which the skin’s natural production of collagen reducing the appearance of wrinkles and fine lines & leading.
  • OUR POTENT MATRIXYL 3000 SIGNALS YOUR SKIN TO INCREASE collagen production for firmer more youthful looking skin. Promotes smooth younger-looking skin with Matrixyl synthe’7 and 1. Argireline helps relax facial muscles and discourages formation of new lines. Let this nutrient rich serum nourish your skin from inside out so your skin can feel vibrant hydrated and healthy looking.
  • CREATES SMOOTHER AND TIGHTER SKIN with our powerful ARGIRELINE peptide also known as the natural treatment. Our fragrance-free moisture rich (non-greasy)serum with collagen and elastin plumps and renews skin leaving it smooth and more elastic.
  • POTENT PEPTIDES FORMULATED IN THE POPULAR HYALURONIC ACID Base to Offer the Best Absorption and Results. Unlike Creams and Oil Based Peptide Solutions That Simply Sit on Top of Skin. It’s natural and organic. Our bottle is not a glass bottle but a professional cosmetic bottle. It will be delivered to you more safely.
  • THE BEST KOREAN SKIN CARE AT THE LOWEST PRICE - You will be hard-set to find the high quality ingredients in our products for even close to our price. We believe fantastic skin-care should be available to anyone, and it is our mission to ensure that you get both top-notch quality products, but also the best customer care available. Contact us anytime through Amazon for assistance.

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Natural Firm & Glow Skincare Set of 3 Serums – Skin Care Products With 20% Vitamin C Serum, Peptide Complex Serum, Niaci... Read Review

  • Hydrating Facial Moisturizer: Hyaluronic Acid is able to hold 1000 times its weight in water, Hyaluronic Acid is the heart of our ultra-hydrating serum! As it restores lost moisture and provides antioxidant defense, it has an incredible plumping effect for softer skin.
  • Brighten the Complexion: With 20% Vitamin C, our anti-aging serum promotes a more flawless complexion! As it prevents and reverses sun damage, it fades sun spots and discoloration for skin that’s brighter and smoother with an undeniable glow.
  • Younger-Looking Skin: When used together, our serums can help clear and smooth your complexion! Hyaluronic Acid aids cell health and elasticity, fading scars and wrinkles, while Vitamin C clears the pores for a more even tone and texture.
  • Quality Ingredients: From improving clarity to maintaining moisture, our face lifting serums provide real results! It’s all thanks to our formulas, which nourish and pamper skin.

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Peptide Complex Serum by Microderm GLO - Best Skin Toning, Facial Tightening, 100% PURE & NATURAL, Plump, Hydrate & Nour... Read Review

  • ❤️ THE #1 SECRET TO HAVING “MAKEUP OPTIONAL” SKIN! Do you want skin so healthy, that you don’t even need to wear makeup to feel confident in your flawless skin? Our Microderm GLO Peptide Complex naturally boosts your skin’s collagen production and promotes youthful firm and tone skin! DERMATOLOGIST RECOMMENDED
  • ❤️ 100% NATURAL SKIN-LOVING INGREDIENTS— Infuse your skin with powerful, healing ingredients that unlock your skin’s natural radiance and youthful firmness! Made with only natural and pure ingredients that your skin with love: Hyaluronic Acid, Aloe Vera, 3x Active Peptides, Japanese Green Tea, and Honeysuckle.
  • ❤️ MADE IN THE USA WITH PURITY… Are you ready for a game-changing skincare serum that restores your skin’s youthful elasticity and firmness? Our Peptide Complex Serum is a concentrated delivery system with three medical-grade active peptides and premium ingredients to naturally boost your skin’s vibrance!
  • ❤️ HEALTHY SKIN IS SEXY! Did you know our Microderm GLO Peptide Complex Serum naturally tones and tightens your skin and reduces blemishes, dark spots, visible pores, and sun damage? Return to youthful, soft, smooth, firm, bouncy, radiant, and sexy skin! It’s never too late to get back to healthy skincare…
  • ❤️ ENJOY OUR “GORGEOUS SKIN IN A BOTTLE” GUARANTEE! Giving you amazing skin results is our top priority! If you don’t see noticeable improvements in the texture and radiance of your skin after using your complete 1 ounce bottle, we will provide you with a full money-back refund! Click the yellow “Add to Cart” button today with total confidence in your results!

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Peptide Complex Serum / Collagen Booster for the Face with Hyaluronic Acid and Chamomile Extract - Anti Aging Peptide Se... Read Review

  • SMOOTHER SKIN – Our proprietary peptide complex, which includes Arginine, Aspartic Acid, Glycine and Alanine, encourages the skin’s natural production of collagen, reducing the appearance of wrinkles and fine lines, and leading to a smoother, healthier-looking skin.
  • REGENERATIVE ACTION – The combination of peptides and concentrated pure chamomile extract, along with Organic Jojoba Seed Oil and Gotu Kola and Horsetail Extracts, helps to accelerate the healing of the skin. The hyaluronic acid acts as a perfect moisturizing complement, keeping the skin looking young and firm.
  • POST PEEL SERUM - Ideal treatment to use after chemical peels (glycolic, salicylic, lactic, TCA) to accelerate generation of collagen and reduce inflammation. Don't peel without it!
  • Please note that all serums can sometimes create irritations for people with very sensitive skin or uncommon allergies. Always test the product on a small area before using it, ideally behind an ear or under the chin. Allow 24 hours to measure skin sensitivity to the product.

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Collagen Peptide Complex Serum By Eva Naturals - Best Anti-Aging Collagen Peptide Serum Reduces Wrinkles, Heals, and Rep... Read Review

  • Collagen Serum: What are Peptides? They're powerful anti-aging proteins that alert skin when it's time to produce more collagen. Our Peptide Serum boasts aloe and hyaluronic acid to smooth away wrinkles and improve elasticity for a stunningly youthful glow.
  • Heal and Repair: In addition to being an anti-aging face serum, peptides are touted as natural healing agents and our Peptide Serum for face is the best on the market!
  • Smooth and Hydrated Skin: Achieving a softer, firmer complexion is easier than you think. Collagen Face Serum is a hydrating serum that uses Hazel and Jojoba to help hydrate and even the skin, providing you with a more even tone. Peptides are known for being rich in antioxidants that fight free radicals and keep you hydrated!This anti aging serum for face will make your face and neck feel soft and supple!
  • Anti Aging Serum For Face: Our Collagen Serum can plump face, skin, and lips, and when skin is firmer and plumper, wrinkles and fine lines will be less visible.
  • Eva Naturals has quickly become one of the most trusted names in plant-based skincare. Our anti aging serum is Cruelty Free, uses plant derived ingredients, and is safe for all skin types!