10 Best Laundry Stain Remover of December 2025

List of Top Rated Laundry Stain Remover from thousands of customer reviews & feedback.

Updated On Dec 2025

448 Reviews Studied

By Customer Ratings

1
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Spray 'N Wash Max Laundry Strain Remover 16 oz Read Review

  • 1st time stain removal
  • Removes tough stains like grease and motor oil
  • Eliminate tough dried-in stains
  • May be used with other laundry additives
  • Safe for all colorfast washables

2
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Zout Laundry Stain Remover - 22 oz - 2 pk Read Review

  • Zout liquid spray remover
  • For a wider variety of fabrics and stains
  • Designed to help break down specific stain types
  • More easily removed in the washer
  • 22 oz Size; pack of 2

3
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Grandma's Secret Spot Remover, 2 Ounce (Pack of 3) Read Review

  • 3 bottles of grandma's Secret spot Remover for all your tough stain removal
  • Each bottle holds 2 ounces of Remover
  • Environmentally safe formula that biodegradable, nontoxic, and contains no chlorine or phosphates.
  • No need to scrub, just apply a drop. . . Won't harm your fabrics.

4
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Dreft Stain Remover, 24 Ounce (Pack of 2) + Dreft Stain Pen Read Review

  • Made for Tough Stains- specially formulated for tough stains on infants' and children's clothing, bedding, and blankets.
  • Plant Based Ingredients (USDA Certified Biobased Product)
  • Hypoallergenic
  • Free of dyes, chlorine, phosphate

5
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Grandma's Secret Laundry Spray, 16-Ounce (Pack of 3) Read Review

  • It’s Like a Washing machine in a bottle!! Have a tough stain... You will never use anything else
  • Just a drop is all you need to remove oil, grease, paint, make-up, grass, clay, ink, blood, baby food, tar, coffee, rust, betadine, pet stains, fabric bleed…..most any stains!
  • And it is versatile. Use on all fabrics, carpet, rugs, pet bedding, even leather.  Amazingly, it even removes old stains as well! Try it on those stains that have aged in, or ones that have gone through the washing machine already
  • The best part is that it is concentrated. Just one 2 oz. bottles can last you up to a year with normal use. Comes with a convenient trigger spray dispenser
  • Environmentally friendly and safe, too. Non-toxic contains no chlorine or phosphates and is biodegradable. Made in the USA

6
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Grandma's Secret 7001 2 Pack Spot Remover Laundry Spray, 16 fl oz, 32 Read Review

  • Works on Oil, Grease, Paint, Make-Up, Grass, Clay, Inks, Blood, Baby Formula, Tar, Spaghetti Sauce, Coffee, Betadine, Rust, Turmeric, Fabric Bleed, Pet Stains.
  • No chlorine, non toxic
  • Biodegradable, saturates easily, penetrates stains
  • Trigger spray dispenser
  • Made in America

7
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OxiClean Laundry Stain Remover Refill, 56 Oz Read Review

  • Tackle the toughest dried in stains
  • Unbeatable on the toughest stains, from red wine and blueberries to chocolate and tomato sauce
  • Oxygen-based, chlorine free and color safe
  • Fast acting
  • Works in all temperatures

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Oxiclean Maxforce Spray Twin Pack (2 Count of 16 Fl Oz Bottles), 32 Fl Oz Read Review

  • Combines 5 types of stain fighters to help you get out more of your toughest dried-in stains the 1st time
  • Great on grass and blood, grease and oil, food stains, soil and clay.
  • Tackles dried-on stains the first time. Machine wash with detergent in the warmest water the fabric will accept. For delicates, hand wash or use the delicate cycle.
  • Treat your clothes now and then wash up to a week later.
  • Contains 2x16 fluid ounces.

9
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Zout Laundry Stain Remover Spray, Triple Enzyme Formula, 22 Ounce Read Review

  • The first enzyme helps remove tough protein stains such as Blood, Grass, and Sweat
  • The second enzyme works on starch stains like Tomato and BBQ Sauces.
  • The third enzyme targets oily stains like Salad Dressing and Margarine.
  • Triple Threat Stains Need Triple Enzyme Formula!
  • This package includes on 22 Ounce bottle of Zout Laundry Stain Remover

10
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Shout Advanced Foaming Grease and Oil Stain Remover for Clothes, 18 oz Read Review

  • The package dimension of the product is 25.9cmL x 6.6cmW x 6.6cmH