10 Best Clothing Stain Remover of December 2025

List of Top Rated Clothing Stain Remover from thousands of customer reviews & feedback.

Updated On Dec 2025

2,444 Reviews Studied

By Customer Ratings

1
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Grandma's Secret Spot Remover, 2 Ounce (Pack of 3) Read Review

  • 3 bottles of grandma's Secret spot Remover for all your tough stain removal
  • Each bottle holds 2 ounces of Remover
  • Environmentally safe formula that biodegradable, nontoxic, and contains no chlorine or phosphates.
  • No need to scrub, just apply a drop. . . Won't harm your fabrics.

2
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Shout Advanced Foaming Grease and Oil Stain Remover for Clothes, 18 oz Read Review

  • The package dimension of the product is 25.9cmL x 6.6cmW x 6.6cmH

3
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Resolve Max Power Pre-Treat Laundry Stain Remover and Maxpower Gel, 6.7 Ounce Read Review

  • Resolve max power pre-treat laundry stain remover
  • Pre-treat laundry stain remover
  • Maxpower gel

4
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Tide To Go Instant Stain Remover, 3 Count Read Review

  • #1 instant stain remover based on sales
  • Powerful solution breaks stains down; microfiber pad lifts and absorbs them
  • Portable, pen-like design – fits neatly into briefcases, purses, drawers, or car compartments
  • No mess, nothing to throw away, nothing to get on hands
  • Works well on tomato juice, ketchup, BBQ sauce, grape juice, coffee, wine, tea, chocolate syrup, and more
  • Doesn't contain bleach
  • Doesn’t contain bleach

5
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Miss Mouth’s Messy Eater Non-Toxic Baby and Kids Stain Remover for Clothing, Carpet, Fabric, and Upholstery. Kid Tested... Read Review

  • SAFE, POWERFUL & FAST – The professional, commercial grade formula is safe around kids & pets. Its lightning fast action erases stains from clothing, bibs, carpets, auto & furniture upholstery
  • NATURAL STAIN REMOVER DESIGNED FOR KIDS – Quickly & safely treats the inevitable stains made by professional mess makers. 5 Star reviews from The Today Show, Good Morning America, & Real Simple
  • NONTOXIC & EFFECTIVE – No peroxide, chlorine, phosphates, sulphates or parabens. 100% biodegradable pH neutral formula is tough on stains, but not on skin or clothes. “Safer Choice” certified
  • WORKS ON ALL KID, BABY & TODDLER STAINS – Universal stain remover is effective on fresh & set-in stains made from fruit, juice, baby food, formula, ketchup, spaghetti sauce, & even blood, 1’s & 2’s
  • CONVENIENT & EASY TO USE – Simply spray, blot, rinse, and watch the fresh or dry stains disappear. Can also be used as a laundry stain remover or bring the wipes with you on the go/ while traveling

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Spray 'N Wash Max Laundry Strain Remover 16 oz Read Review

  • 1st time stain removal
  • Removes tough stains like grease and motor oil
  • Eliminate tough dried-in stains
  • May be used with other laundry additives
  • Safe for all colorfast washables

8
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Zout Laundry Stain Remover Spray, Triple Enzyme Formula, 22 Ounce Read Review

  • The first enzyme helps remove tough protein stains such as Blood, Grass, and Sweat
  • The second enzyme works on starch stains like Tomato and BBQ Sauces.
  • The third enzyme targets oily stains like Salad Dressing and Margarine.
  • Triple Threat Stains Need Triple Enzyme Formula!
  • This package includes on 22 Ounce bottle of Zout Laundry Stain Remover

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Oxiclean Maxforce Spray Twin Pack (2 Count of 16 Fl Oz Bottles), 32 Fl Oz Read Review

  • Combines 5 types of stain fighters to help you get out more of your toughest dried-in stains the 1st time
  • Great on grass and blood, grease and oil, food stains, soil and clay.
  • Tackles dried-on stains the first time. Machine wash with detergent in the warmest water the fabric will accept. For delicates, hand wash or use the delicate cycle.
  • Treat your clothes now and then wash up to a week later.
  • Contains 2x16 fluid ounces.

10
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The Laundress - Stain Solution, Unscented, Clothing Stain Remover, Baby Stains and Blood Spots on Laundry, Liquid Spot R... Read Review

  • CONQUER TOUGH STAINS: Just a few drops lifts old and new protein and tannin-based stains such as coffee, tea, ink, juice, wine, grass, blood, urine, and pit stains
  • FOR ALL COLORS & FABRICS: Use on whites, darks, and colors and all washable fabrics
  • HIGHLY CONCENTRATED FORMULA: A little goes a long way
  • ECO-FRIENDLY: Made with only plant-based, biodegradable ingredients. Free of dyes, unnecessary additives, and fillers
  • CRUELTY FREE: The Laundress products are always tested on our founders, Gwen and Lindsey, and never on animals ; Nontoxic ; allergen-free.