10 Best Ergonomic Mouse For Wrist Pain of August 2025

• ✅ ERGONOMIC DESIGN – The unique ergonomic shape supports the palm, with an innovative vertical design that keeps your hand and arm in a more natural and comfortable position. Effectively reduces wrist strain and pain compared to a traditional mouse.
• ✅ STABLE CONNECTION WITH LESS NOISE CLICK – Reliable 2.4G wireless mouse connection with high anti-interference performance with 33ft transmission distance. Quieter click makes you concentrate on the work without disturbing others beside you. Just Plug and Play.
• ✅ MULTIFUNCTION AND CONVENIENT -- Advanced "Page Back" and "Page Forward" functionality buttons provide convenience when web page browsing. 1000 /1200/1600 DPI Levels -- Easily adjusts the sensitivity of the mouse.
• ✅ WIDE COMPATIBILITY – Widely compatible with Windows 2000 / XP / Vista / 7 / 8 / 10 / Linux. 【Note: computer needs to have a USB receiving port】 Once you get used to the ergonomic mouse, you will love it so muc!
• ✅ GREAT CUSTOMER SERVICE -- Rest assured that all our ASOI ergonomic vertical mouse have unconditional 18-month product warranty ( Replace or Refund ) as well as lifetime easy-to-reach technical support.

ASOI

• Great Ergonomic Design: Hold this vertical mouse in a natural handshake position, prevent wrist pain/strain from long time use. More comfortable, more efficient on Work.
• 3 Connection Options: This vertical mouse has 3 connection mode: BT 4.0, BT4.0, and 2.4G. easy control 3 devices at the same time. Switch freely between Android, tablet and Mac with just a click.
• Wide Compatiblity: Bluetooth enabled devices with Windows / Android / MAC OS/iPad iOS system, 2.4G wireless mode supports all devices with usb port. Fits for PC, lapotop, tablet, Mac, cellphone. Note: The USB receiver is stored in battery compartment of the mouse.
• Sensitive Tracking: 1000, 1600 and 2400 DPI can Better meet your needs. More sensitivity than standard optical mouse for smooth and accurate tracking on a wide range of surfaces.
• Silent Click & Power Saving: Noiseless, sensitive click help you fully focus on work without disturbing others. Auto sleep to save power if no operation for 30 minutes.

Jelly Comb

• 【Ergonomically Designed Vertical Mouse】 ✍ Designed for neutral "handshake" wrist and arm positions, enabling smooth movements and less overall pressure to reduce wrist pain.
• 【USB Wireless Mouse and Removable Palm Rest】 ✍To avoid the trouble of being tied by wires or cables, the wireless ergonomic mouse comes with a simple plug and play device. The mouse comes with a palm rest that can be easily removed according to user preferences and convenience under.
• 【Adjustable DPI Level】✍The ergonomic computer mouse DPI Resolution Polling: 800-1200-1600-3200 to adjust the responsiveness of the mouse according to your needs and / or preferences. Optical tracking technology ensures higher sensitivity for precise tracking on a variety of surfaces.
• 【Thumb Button and RGB LED LIGHT】✍ Use the back / forward button near the thumb area for best convenience. Adjustable RGB led light, different color conversion is suitable for use at night.
• 【Easy to Installation】✍ Charge the battery, turn on the vertical mouse(ON/OFF switch located on botton of mouse) and attach palm rest(optional). Plug the USB nano receiver into the USB port of your computer. Once the computer recognizes the mouse, you're ready to use.

eirix

• 【ERGONOMIC DESIGN & SUPERB COMFORT】The soft slow rebsound memory foam-filled cushion keeps hand in natural position, providing maximum comfort for office or home use. It reduces wrist irritation and wrist pain. Keeps your hand in a neutral position for ergonomic comfort.Designed to help reduce pressure for maximum comfort and long time use.The mouse pad measures in a medium size, perfect for use without taking up office space.
• 【SMOOTH LYCRA COVERING】Special treatment with 240°F in high pressure chamber, Premium-textured and high-quality Lycra cloth super smooth surface allows more accurate mouse movement to ensure smoother mouse control and pinpoint accuracy. The smooth Lycra covering improves tracking movements and creates consistent gliding. It allows the cursor to move around quickly without stability or cause pain or fatigue in your hand.
• 【NON-SLIP PU BASE & ENVIRONMENTAL】Made of environmental material with ROHS Certificate to ensure safety. Mouse pad is environmental, non-toxic, no-smell and safe to use.The soft non-skid PU base grips the desktop firmly. preventing sliding to offer you stable operation and allowing you to freely move your mouse without interruption. Double-stick and press-process edges to provide flat and smooth edges that won't roll up or separate.It will never move from your desktop until you peel it off.
• 【EXCELLENT SHAPE AND SIZE】Wrist support mouse pad: 9.85 x 7.87 x 0.85 inches & 7.0oz, Keyboard wrist support: 16.9 x 3.54 x 0.85 inches & 4.9oz. Excellent texture. Designed with an optimal shape and size. You can move the mouse around easily and the pad shapes it well. Moreover, the reinforced edges prevent deformation and damage to long time use. Perfect size for work and game.Great gift idea for girls, coworkers, Moms, Birthday, Back to School, Valentine's Day, Easter Day, Mother's Day, Labor

ITNRSIIET

• Ergonomic Design: A mouse mat set designed with soft breathable fabric and premium memory foam, super lightweight, comfortable and durable for your daily work or life. Provides a soothing sensation and relaxation while typing, release the accumulated tension, engineered to prevent injuries of the wrist or hand.
• Optimal Size: Wrist mouse pad (7.95in x 9.92in), keyboard support mouse pad (3.34in x 18.11in), making this pad set suitable for both man/women, all kind of occasion like working, meeting, gaming or other. Note: Please kind understand that the keyboard pad may need several minutes to bounce back to its origin as the package issues, and it won’t affect your use.
• Excellent Quality: The smooth fabric will allow you ease moving your mouse meanwhile precise positioning, give your hand a cosy environment to operate your mouse. Edges has been reinforced to prevent deformation and damage to guarantee the longer hours of use. The soft memory foam-filled cushion part will slowly bounce back when your hand leave it, not easy to out of shape.
• Anti-Slip Rubber Base: Applied anti-skid rubber on the bottom part to escape unwanted move, it will strongly grasp the desk so that you will never be disturbed by the accident move of your mouse, you can concentrate your minds on the work.
• Elegant Look. Any pattern of our mouse pads are carefully handpicked to ensure its superb look, it will add more color to your working or gaming environment. Easy craft but really meet all your needs, you will be impressed by our wrist rest pad set!

iLeadon

• Comfortable Gel Filling: The ergonomic soft gel-filled wrist rest provides good touch and effective support to your wrist. Our gel mouse pad reduces wrist stress that can lead to repetitive motion disorders. (The gel pad is encased under the High-quality Lycra cloth, so it isn't sticky like other gel mouse pads)
• Smooth Fabric Covering: Special treatment with 230°F in high pressure chamber, our premium-textured and high-quality Lycra cloth super smooth surface allow more accurate mouse movement to ensure smoother mouse control and pinpoint accuracy. Mouse pads work well on wired, wireless, optical, and mechanical mice.
• Grips Desktop Firmly: The soft non-skid PU base grips the desktop firmly, preventing sliding to offer you stable operation and allowing you to freely move your mouse without interruption, no need to worry about the mouse pad slipping away.
• Excellent Shape and Size: Designed with an optimal shape and size. You can move the mouse around easily and the pad shapes it well. Moreover, the reinforced edges prevent deformation and damage to guarantee long term use.
• Risk Free Purchase: Any Gel Leak or Wrist Support issue? Contact us, Full Refund & Replacement service is waiting for you (No Return Required). 18-Months 100% Satisfaction Money Back Guarantee. We are committed to our 100% customer satisfaction; if you are not happy, please don’t hesitate to contact with us. We don't sell in Australia.

MROCO

• Unique ergonomic design with removable palm rest to reduce hand and wrist pain
• Two thumb buttons can be used for back/forward browser navigation
• Driver free 3-mode DPI shift:600/1000/1600DPI adjustable
• High-resolution optical sensor with adjustable sensitivity for accuracy and responsiveness
• Scroll Wheel lifetime:200,000 circles/ Button lifetime:3 million times

J-Tech Digital

• GOODBYE TO ALL WRIST PAINS EVEN AFTER LONG HOURS AT YOUR COMPUTER - This ergonomically designed mouse pad will prevent and treat all your wrist aches, soreness and carpal tunnel syndrome encountered by cheaper mouse pads.
• HIGH COMFORT SCROLLING & CLICKING - This high-quality rest pad cushion made with ‘memory foam’ will conform to your natural curve of wrist and hand thus ensuring MAX comfort. The foam has another big advantage that it will easily bounce back into shape after hours of use.
• EXTREME PRECISION & FIRM GRIP TO YOUR DESKTOP - We have combined the best of materials to ensure you get the max precision. The surface is T-cloth to get pinpoint precision and easy tracking movement. The base material is Anti-skid PU base to ensure that the pad isn’t moving around on your desktop.
• EXCELLENT SHAPE AND SIZE WITH REINFORCED EDGES - The reinforced edges will ensure that your mouse never falls of the mat and that the materials won’t peel off.
• HIGH QUALITY MOUSE PAD BACKED BY A 3-YEAR WARRANTY - Unlike many of our competitors we feel confident in providing a 3- year warranty if anything goes wrong. If you want no compromise in quality ‘J&G Mouse Pad’ is the one to purchase!

J&G MODERN COMPUTER ACCESSORIES

• Made of improved Super Soft & Smooth & Breathable Material and Comfortable Memory Foam to the pads, supply Lightweight, Comfortable, Durable and Ergonomic touch, slow bounces back and not easy to out of shape and Ideal for Longer Hours of Use
• Non-skid Rubber base provides heavy grip preventing sliding or unwanted movement for Keyboard and mouse pads, Double Sticking and Press handing for edge to supply flat and smooth edge and will not roll up nor split open;
• Large Mouse Pad size 10 *8.6*1 inch and 17*3*1 inch keyboard wrist pad fits most computers or notebooks or mouse, improve hand and wrist posture, avoid joint and wrist problems and release your elbows and shoulder stress for long hours of use on the computer;
• Mouse Pad adding wrist rest designed with groove fits your hand better; Deformation free keyboard pad, stands still while typing, Relaxing and comfortable use such as home, office, cybercafé, etc.
• If you have any questions about products, we will try our best to provide solution for you within hours.

Gimars

• √ ERGONOMIC DESIGN – Designed to be utilized in neutral "handshake" wrist and arm positions for smoother movement and less overall strain helping alleviate wrist pain.
• √ REMOVABLE PALM REST & BLUE LED TRIM – This mouse comes included with a palm rest that can be easily detached based on the user's preference and convenience. It also features a blue LED, which lights up the outlining of the mouse.
• √ ADJUSTABLE DPI – Switch between DPI levels 800, 1200 and 1600 to adjust mouse responsiveness depending on your need and/or preference. Optical Tracking Technology ensures greater sensitivity for precise tracking on a wide range of surfaces.
• √ THUMB BUTTONS – Use the back/forward buttons located near the thumb area for optimum convenience, (button functionality can also be changed and reassigned using a compatible driver or software).
• √ WIDE COMPATIBILITY & FREE LIFETIME SUPPORT – Compatible with Windows 7/8/10, XP, Vista 7/8 and Linux etc. All J-Tech Digital Products include a One-Year Manufacturer Warranty and free lifetime technical support from our Customer Support Team located in Houston, Texas - Available M-F 9AM-6PM CST - Contact information available on the J-Tech Digital Seller Page.

J-Tech Digital