10 Best Ergonomic Mouse of August 2025

• Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
• 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
• Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
• Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
• Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.

Anker

• ✅ ERGONOMIC DESIGN – The unique ergonomic shape supports the palm, with an innovative vertical design that keeps your hand and arm in a more natural and comfortable position. Effectively reduces wrist strain and pain compared to a traditional mouse.
• ✅ STABLE CONNECTION WITH LESS NOISE CLICK – Reliable 2.4G wireless mouse connection with high anti-interference performance with 33ft transmission distance. Quieter click makes you concentrate on the work without disturbing others beside you. Just Plug and Play.
• ✅ MULTIFUNCTION AND CONVENIENT -- Advanced "Page Back" and "Page Forward" functionality buttons provide convenience when web page browsing. 1000 /1200/1600 DPI Levels -- Easily adjusts the sensitivity of the mouse.
• ✅ WIDE COMPATIBILITY – Widely compatible with Windows 2000 / XP / Vista / 7 / 8 / 10 / Linux. 【Note: computer needs to have a USB receiving port】 Once you get used to the ergonomic mouse, you will love it so muc!
• ✅ GREAT CUSTOMER SERVICE -- Rest assured that all our ASOI ergonomic vertical mouse have unconditional 18-month product warranty ( Replace or Refund ) as well as lifetime easy-to-reach technical support.

ASOI

• Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
• 1000/1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
• Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
• 1.5m/4.9ft USB cable length, product dimensions: 120*62.8*74.8 mm; product weight: 5.3 oz.
• Package includes: 1 Anker Vertical Ergonomic Optical Mouse (with 4.9 ft cable), 1 instruction manual. Includes 18 month warranty and lifetime technical support guarantee.

Anker

• Wide Compatibilty: Bluetooth mode supports Bluetooth enabled devices with Windows / Android / Mac OS system. 2.4G wireless mode supports all devices with usb port. Fits for PC, laptop, cellphone, Mac. Added forward/ backward buttons provide convenience when webpage browsing. NOTE: Forward/backward buttons will not work on Mac
• Bluetooth & 2.4G Wireless Connection: This ergonomic mouse has dual connection modes BT 4.0 and 2.4G RF (USB Nano Receiver stored in the mouse bottom), you can control two devices at the same time, switch freely between Android, tablet and Mac with just one button
• Advanced Ergonomic Design: The ergonomic design places your hand in a natural handshake position and offers your hand maximum support for lasting comfort. Concave area for Thumb and little extended bottom edge for pinky finger, smoother moving and more comfortable grip. Effectively reduces the wrist strain and pain
• Silent Click & Adjustable DPI: Quiet clicks can bring a better user experience and free your worry about bothering others and keep you stay focused while working. 3 adjustable DPI levels (1000/1600/2400) allows you to change the cursor sensitivity easily depending on your activity and track more smoothly over a variety of surfaces
• Exquisite & Warranty: It has an elegant rubbery matte finish that provides a nice grip, while resisting fingerprints and smudges. Every Jelly Comb product includes 12-month warranty. If you have problems with product, please contact us to solve it for you

Jelly Comb

• Stop chasing a mouse around. Your trackball stays in one place and puts control under your thumb, so you don't have to move your arm to move your cursor. And its sculpted shape supports your hand for comfortable control all day long.
• This trackball includes the Logitech unifying receiver. The tiny wireless receiver stays in your laptop, so there's no need to unplug it when you move around. Plus, you can easily add a compatible keyboard, number pad or mouse-without the hassle of multiple USB receivers.
• You can go for up to 18 months without changing batteries and the convenient battery indicator helps to ensure that you'll never be caught off guard. Battery life may vary based on user and computing conditions.
• You get precise cursor control wherever you want to use your trackball. Hard tables, comfy sofas and lumpy beds are all no problem for the M570.
• The integrated scroll wheel and easy-to-reach back/forward buttons make control simple, whether you're web surfing on a laptop or navigating a home-theater PC.
• Stop chasing a mouse around. Your trackball stays in one place and puts control under your thumb, so you don't have to move your arm to move your cursor. And its sculpted shape supports your hand for comfortable control all day long.
• Note: In case of wireless mouse, the USB receiver will be provided inside or along with the mouse
• This trackball includes the Logitech Unifying receiver. The tiny wireless receiver stays in your laptop, so there's no need to unplug it when you move around. Plus, you can easily add a compatible keyboard, number pad or mouse-without the hassle of multiple USB receivers.
• You can go for up to 18 months without changing batteries and the convenient battery indicator helps to ensure that you'll never be caught off guard. Battery life may vary based on user and computing conditions.
• You get precise cursor control wherever you want to use your trackball. Hard tables, comfy sofas and lumpy beds are all no problem for the M570.

Logitech

• ADVANCED ERGONOMIC DESIGN - Places your hand in a natural handshake position using a unique 57-degree angle, preventing forearm twisting and reducing muscular strain by 10 percent* (*As compared with a traditional non-vertical mouse. Based on Logitech Study, September 2017)
• HYPER-EFFICIENT TRACKING - 4000 DPI high-precision sensor provides precise tracking that requires 4x less hand movement compared to a traditional mouse with a 1000 DPI sensor
• CROSS-COMPUTER CONTROL - Game-changing capacity to navigate seamlessly on three computers, and copy-paste text, images, and files from one to the other using Logitech FLOW
• THREE WAYS TO CONNECT - Use with up to three Windows or Mac computers via included wireless USB unifying receiver or Bluetooth smart technology or the included USB-C charging cable
• RECHARGEABLE BATTERY - With quick charging: Stays powered for 4 months on a full charge – and get 3 hours of use from a 1-minute quick charge (Battery life may vary based on user and computing conditions)
• ADVANCED ERGONOMIC DESIGN - Places your hand in a natural handshake position using a unique 57-degree angle, preventing forearm twisting and reducing muscular strain by 10 percent* (*As compared with a traditional non-vertical mouse. Based on Logitech Study, September 2017)
• Note : In case of Wireless mouse, the USB receiver will be provided inside or along with the mouse
• HYPER-EFFICIENT TRACKING - 4000 DPI high-precision sensor provides precise tracking that requires 4x less hand movement compared to a traditional mouse with a 1000 DPI sensor
• CROSS-COMPUTER CONTROL - Game-changing capacity to navigate seamlessly on three computers, and copy-paste text, images, and files from one to the other using Logitech FLOW
• THREE WAYS TO CONNECT - Use with up to three Windows or Mac computers via included wireless USB unifying receiver or Bluetooth smart technology or the included USB-C charging cable

Logitech

• ✔ ERGONOMIC, SLEEK AND RECHARGEABLE DESIGN -- Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain
• ✔ MULTIFUNCTION AND CONVENIENT -- Advanced "Page Back" and "Page Forward" functionality buttons provide convenience when web page browsing. 800 /1200/1600 DPI Levels -- Easily adjusts the sensitivity of the mouse
• ✔ HIGH-CAPACITY RECHARGEABLE BATTERY -- Built-in rechargeable battery. You no longer need to buy batteries, very convenient !! EASY TO USE -- One nano USB receiver at the bottom of mouse, Just Plug and Play!
• ✔ WIDELY COMPATIBLE -- Widely compatible with Windows 2000 / XP / Vista / 7 / 8 / 10 / Linux. 【Note: Not compatible with Mac OS, Apple Products】 Once you get used to the ergonomic mouse, you will love it so much !
• ✔ GREAT CUSTOMER SERVICE -- Rest assured that all our LEKVEY ergonomic vertical mouse have unconditional 18-month product warranty ( Replace or Refund ) as well as lifetime easy-to-reach technical support

LEKVEY

ASOI

• Ergonomic Design Mouse -- The shape of this Bluetooth Mouse keeps your hand in the right ergonomic position, end of wrist & shoulder pain
• 1 Mouse for Multi-purpose -- Connects up to 3 devices via Bluetooth 5.0 + Bluetooth 3.0 + 2.4G wireless, 1 click for switch from the devices easily
• Noiseless Click & Voiced Click -- Equipped with 9 buttons, featuring with noiseless click & voiced click left/right button to meet your different needs for working or gaming
• Rechargeable Mouse -- With built-in rechargeable battery which means you can use this mouse without running the risk of not having a couple of batteries at hand
• Wide Compatibility -- Bluetooth and 2.4G wireless connectivity make this mouse supports almost all Bluetooth-enabled devices or the devices with USB ports

seenda

• 𝐄𝐫𝐠𝐨𝐧𝐨𝐦𝐢𝐜 𝐖𝐢𝐫𝐞𝐥𝐞𝐬𝐬 𝐃𝐞𝐬𝐢𝐠𝐧 – The J-Tech Digital V638's comfortable, ergonomic "handshake" design greatly reduces arm/wrist/hand strain. Back/forward thumb buttons provide extra convenience. (Button functionality can also be changed or reassigned using third party software.) Works on most non-metallic surfaces. The built-in lithium battery is fully rechargeable.
• 𝐑𝐞𝐦𝐨𝐯𝐚𝐛𝐥𝐞 𝐏𝐚𝐥𝐦 𝐑𝐞𝐬𝐭 – This ergonomic mouse features a detachable non-skid anti-sweat palm rest that reduces drag, making it easier to maneuver the mouse across the surface of a mousepad, tabletop, desktop, etc.
• 𝐀𝐝𝐣𝐮𝐬𝐭𝐚𝐛𝐥𝐞 𝐃𝐏𝐈 – Users can adjust responsiveness to 800, 1200, 1600 or 3200 DPI depending on their need and/or preference. 360-degree signal allows for full freedom of ergonomic mouse movement. Optical Tracking Technology ensures greater sensitivity for precise tracking on a wide range of surfaces.
• 𝐖𝐢𝐝𝐞 𝐂𝐨𝐦𝐩𝐚𝐭𝐢𝐛𝐢𝐥𝐢𝐭𝐲 – Compatible with Windows 7/8/10, XP, Vista 7/8, Linux, Mac OS, etc. A USB Nano Receiver/Dongle Transceiver connects the ergonomic mouse wirelessly to your computer, so you aren’t tethered by a cable.
• 𝐅𝐫𝐞𝐞 𝐋𝐢𝐟𝐞𝐭𝐢𝐦𝐞 𝐒𝐮𝐩𝐩𝐨𝐫𝐭 – The V638 ergonomic mouse, like all J-Tech Digital Products, includes a One-Year Manufacturer Warranty and free lifetime technical support from our US based Customer Support Team (Available M-F 9AM-6PM CST). Contact information available on the J-Tech Digital Seller Page.

J-Tech Digital