10 Best Wireless Mouse For Large Hands of August 2025

List of Top Rated Wireless Mouse For Large Hands from thousands of customer reviews & feedback.

Updated On Aug 2025

3,000 Reviews Studied

By Customer Ratings

1
Image
Logitech M525 Wireless Mouse – Long 3 Year Battery Life, Ergonomic Shape for Right or Left Hand Use, Micro-Precision Scr... Read Review

  • ERGONOMIC SHAPE - Ergonomically shaped design and soft rubber grips conform to your hand to be naturally comfortable and the compact size makes it easy to take with you wherever you use your computer at home, at work or anywhere else, USB receiver is stored inside the mouse where the batteries are located
  • Interface: USB receiver. Mouse Dimensions (height x width x depth)-4.00 x 2.24 x 1.51 inches. Receiver Dimensions (height x width x depth)-0.57 x 0.74 x 0.24 inches
  • CONVENIENT CONTROLS - Easy-to-reach Back/Forward buttons makes moving quickly between documents or browsing your favorite Web sites a breeze
  • MICRO-PRECISE SCROLL WHEEL - With more grooves per millimeter, our new scroll wheel gives you the ultimate navigation experience
  • LONG BATTERY LIFE - 3 year battery life and smart sleep mode help you go longer between battery changes
  • PLUG'N'PLAY CONNECTION - Nano-sized Logitech wireless unifying receiver stays in your computer plug it in, forget it, even add compatible wireless devices without multiple USB receivers

2
Image
Logitech M570 Wireless Trackball Mouse – Ergonomic Design with Sculpted Right-Hand Shape, Compatible with Apple Mac and... Read Review

  • Stop chasing a mouse around. Your trackball stays in one place and puts control under your thumb, so you don't have to move your arm to move your cursor. And its sculpted shape supports your hand for comfortable control all day long.
  • This trackball includes the Logitech unifying receiver. The tiny wireless receiver stays in your laptop, so there's no need to unplug it when you move around. Plus, you can easily add a compatible keyboard, number pad or mouse-without the hassle of multiple USB receivers.
  • You can go for up to 18 months without changing batteries and the convenient battery indicator helps to ensure that you'll never be caught off guard. Battery life may vary based on user and computing conditions.
  • You get precise cursor control wherever you want to use your trackball. Hard tables, comfy sofas and lumpy beds are all no problem for the M570.
  • The integrated scroll wheel and easy-to-reach back/forward buttons make control simple, whether you're web surfing on a laptop or navigating a home-theater PC.
  • Stop chasing a mouse around. Your trackball stays in one place and puts control under your thumb, so you don't have to move your arm to move your cursor. And its sculpted shape supports your hand for comfortable control all day long.
  • Note: In case of wireless mouse, the USB receiver will be provided inside or along with the mouse
  • This trackball includes the Logitech Unifying receiver. The tiny wireless receiver stays in your laptop, so there's no need to unplug it when you move around. Plus, you can easily add a compatible keyboard, number pad or mouse-without the hassle of multiple USB receivers.
  • You can go for up to 18 months without changing batteries and the convenient battery indicator helps to ensure that you'll never be caught off guard. Battery life may vary based on user and computing conditions.
  • You get precise cursor control wherever you want to use your trackball. Hard tables, comfy sofas and lumpy beds are all no problem for the M570.

3
Image
VicTsing MM057 2.4G Wireless Portable Mobile Mouse Optical Mice with USB Receiver, 5 Adjustable DPI Levels, 6 Buttons fo... Read Review

  • Comfortable Ergonomic DesignAfter thousands of samples of palm data we designed this ergonomic mouse. The mouse has a streamlined arc and thumb rest to help reduce the stress caused by prolonged use of the mouse. The side pits help reduce slippage and maximize your feeling of use!
  • Save Battery LifeUp to 15 months battery life you don't need to worry about changing batteries frequently! This computer optical mouse will be in sleep mode in 8 minutes of inactivity. Press any button to wake it up. Note: powered by 1AA battery (not included).
  • Easy to UseNo need any driver and you can plug and play the wireless mouse directly. Plug and play! This computer mouse support 33ft wireless connections you can avoid being bothered by the power cord and use this mouse anytime anywhere.
  • Multi-function Wireless Mouse5 levels DPI: 800/1200/1600/2000/2400 easily change the cursor sensitivity depending on your activity. Two side buttons that you can use to control page forward/backward for increased productivity. Advanced technology help mouse moves around the computer screen smoothly!
  • Wide CompatibilityWell compatible with Windows7/8/10/XP Vista7/8 and Linux etc. Fits for desktop laptop PC Macbook and other devices. A universal portable mouse designed for office family travel business meetings etc.!
  • Operating system: Windows 7

4
Image
Logitech M510 Wireless Computer Mouse – Comfortable Shape with USB Unifying Receiver, with Back/Forward Buttons and Side... Read Review

  • Your hand can relax in comfort hour after hour with this ergonomically designed mouse. Its contoured shape with soft rubber grips, gently curved sides and broad Palm area give you the support you need for effortless control all day long.
  • You've got the control to do more, Faster. Flipping through photo albums and web pages is a breeze, especially for right-hander three standard buttons plus back/forward buttons that you can also program to switch applications, go full screen and more. And side-to-side scrolling Plus zoom gives you the power to scroll horizontally and vertically through your music library, maps and Facebook feeds, and zoom in and out of photos and budget spreadsheets with a click.
  • Two years of battery life practically eliminates the need to replace batteries. ** the on/off switch helps conserve power, smart sleep mode extends battery life and an indicator light eliminates surprises. ** Battery life may vary based on user and computing conditions.
  • The tiny Logitech Unifying receiver stays in your laptop. There's no need to unplug it when you move around, so there's less worry of it being lost. And you can easily add compatible wireless mice and keyboards to the same wireless receiver.

5
Image
ELECOM Dr.EXG Wireless Mouse 2.4GHz 5 Buttons BlueLED Less Click Noise Mouse/Ergonomic Design/Back Forward Button 2000 D... Read Review

  • 【FUNCTIONAL 5 BUTTONS & LESS NOISE CLICKING SOUND】 It is very easy to move in any direction. It comes with 5 physical buttons on the device, includes BACK BUTTON which is convenient for web browsing. ELECOM Mouse Assistant Software can be easy to customize button functions that include PRESENTATION SLIDES CONTROL BUTTONS. ELECOM Mouse Assistant Software will be available to download from ELECOM NET website.
  • 【BLUE LED SENSOR】 Blue LED outperforms both optical and laser mice. The combination of a large beam with image sensors and pixel geometry allows the mouse to track accurately on almost any surface.
  • 【2000 HIGH RESOLUTION】 2000 High-definition (DPI) optical tracking enables responsive cursor control for precise tracking and easy text selection allowing precise mouse movement.
  • 【PLUG & PLAY - NO INSTALLATION REQUIRED】 No need to install any software or driver. Simply just connect via Bluetooth and ready to go!! It works for Windows & macOS
  • 【PRODUCT DETAILS】 Compatible with Windows 10, Windows 8.1, Windows7, macOS Catalina(10.15), Size82mm/3.2inch (W) × 119.9mm/4.7inch (D) × 42mm/1.7inch (H), Weight87g/3.1oz (includes battery), DPI2000 count, Connectivity2.4G Wireless Connection, 1 X AA battery(Included)- Battery Remaining Light Lamp equipped. The back of mouse has a ON/OFF switch and it saves the buttery power when you don't use it.

6
Image
TeckNet Pro 2.4G Ergonomic Wireless Optical Mouse with USB Nano Receiver for Laptop,PC,Computer,Chromebook,Notebook,6 Bu... Read Review

  • Plug & Play - Comes with a tiny USB Nano receiver(stored within the back of the mouse) , just plug it into your PC and then forget it. 5 Adjustable DPI Level (2600/2000/1600/1200/800) - choose your own cursor speed
  • Hassle-free Design - Up to 24-months battery life with a battery level indicator. Smart auto-sleep mode saves power (battery life may vary based on user and computing conditions)
  • TeckNet Tru-Wave technology provides precise, smart cursor control over many surface types. TeckNet Co-Link technology – after pairing there’s no need to re-establish pairing after a signal loss or shutdown
  • 2.4GHz Wireless - ensures reliable connection with an increased working distance of up to 33/10m and eliminates delays, dropouts and interference. Contoured shape with soft rubber grips provide all-day comfort
  • Compatible with Windows XP, Vista, 7, 8, 8.1,10 and Linux. Works with Notebook,Chromebook, PC, Laptop, Computer, and more.(batteries are NOT included)

7
Image
Logitech M510 Wireless Mouse-Black (Renewed) Read Review

  • This Certified Refurbished product is tested & certified to work like-new. The product is backed by a 90 day warranty
  • Contoured shape with soft rubber grips provide all-day comfort
  • Back/forward buttons and side-to-side scrolling plus zoom let you do more, faster Requires Logitech SetPoint software
  • 2-year battery life practically eliminates the need to replace batteries Battery life may vary based on user and computing conditions
  • Comes with a tiny Logitech Unifying receiver that stays in your computer - plug it in, forget it

8
Image
Evoluent VM4SW VerticalMouse 4 Right Hand Ergonomic Mouse with Wireless Connection (Small Size) Read Review

  • PREVENTS WRIST DISCOMFORT - Evoluent's ergonomic VM4SW VerticalMouse 4 gently supports your right hand in an upright neutral position. The patented shape prevents you from twisting your forearm like what you usually do with an ordinary mouse.
  • PROGRAM YOUR MOUSE TO YOUR NEEDS - Install the Evoluent Mouse Manager onto your computer to configure the VerticalMouse's buttons. Not only can you change their function but you can also set how the buttons work within different programs.
  • ADJUST MOUSE-SPEED FROM LOW TO HIGH - You can adjust the pointer speed from low to high with the optical sensor controls on the side of the mouse. There is no need to release the grip for speed adjustment.
  • OFFERS OPTIMUM COMFORT - The VerticalMouse 4 has a broader lip along the bottom edge that prevents the pinky finger from rubbing the desk. The thumb has been reshaped from earlier version to provide more comfort
  • HARDWARE COMPATIBILITY: VerticalMouse is plug-n-play compatible with all operating systems that support USB. Basic button and wheel functions work without additional drivers. SOFTWARE COMPATIBILITY: VerticalMouse comes with Mouse Manager software for customizing the buttons. Mouse Manager is compatible with: Windows 7 and 10 Mac OS 10.5 to 10.14 (update for 10.15 is under development. Third party software may be used in place of Mouse Manager for OS 10.15.)

9
Image
Logitech MX Master 3 Advanced Wireless Mouse Read Review

  • MAGSPEED WHEEL: Ultra-fast, precise, quiet MagSpeed electromagnetic scrolling
  • DARKFIELD 4000 DPI SENSOR: Darkfield 4000 DPI sensor for precise tracking on any surface, even glass (up to 4mm in thickness)
  • COMFORTABLE DESIGN: Tactile reference for hand positioning makes it easy to stay oriented and in your flow
  • FLOW CROSS-COMPUTER CONTROL: Supports flow cross-computer control across multiple screens. Pair up to 3 devices via Bluetooth Low Energy or Unifying USB receiver

10
Image
Memzuoix Wireless Ergonomic Mouse, Upgraded 2.4G Optical Cordless Mice with 800 / 1200 /1600 DPI, Vertical Computer Wire... Read Review

  • 【ERGONOMIC, VERTICAL AND FRIENDLY FOR YOUR RIGHT-HAND, LARGE】The upgraded proper optical ergonomic design keeps your hand and arm staying more naturally. The ergonomic shape design encourages healthy neutral "handshake" wrist and arm positions. Effectively smoother movement and less overall strain, compared with a regular wireless mouse. (Note: It's not for Your Left-Hand)
  • 【 EASY TO USE,CONVENIENT AND''ON/OFF'SWITCH DESIGN 】One nano USB receiver at the bottom of the battery compartment, Just Plug and Play! This ergonomic wireless mouse is friendly for large hands, if the small hands and you never used any kind of this mouse, it will take several days to get used to. With 2.4G wireless connection. It needs to install 2*AAA Dry Batteries(Not Included)!! Also the'' On/Off' switch design, reliable battery life solves the trouble of changing battery frequently.
  • 【ADJUSTABLE 3 DPI LEVELS& MULTIFUNCTION】With adjustable 3 DPI levels 800/1600/2400, Our optical mouse enables you to adjust DPI by DPI button whenever you want. It’s also constructed with 6 buttons with multifunctional functions to improve productivity and efficiency in daily work...
  • 【WIDELY COMPATIBLE】Compatible with Windows 8/7/10/Vista/XP/2000, Mac, Linux \\If you are using a Linux, because of the different needs of its kernel, you need to set related software of the requirements, this ergonomic mouse will be used normally.// (NOTE: Both forward and backward buttons are not recognized on Mac).