10 Best Over The Counter Muscle Relaxer of December 2025

• Dee Cee Laboratories Formula 303 Natural Muscle Relaxant, 45 Tablets

Dee Cee Laboratories

• Formula 303 contains a time-tested combination of NATURAL ingredients that works FAST
• Formula 303 for Muscle Cramps, Back Pain, Tension Relief
• No Sugar, No coloring--All Natural ingredients

Dee Cee Laboratories

• Provides extra strength pain relief for aching back
• Doan's pills have been relieving back pain for millions of backache sufferers for generations
• Doan's active ingredients target the muscles of the back and ease the pain

Doans

• Effective Relief Supplement: Relieve-R is formulated to address everyday aches and discomfort, without habit-forming ingredients.
• Feel More Relaxed: Customers typically feel a decrease in discomfort and muscle tension, and an increase in relaxation—often in less than 30 minutes. Effects are reportedly better than, or similar to, typical over-the-counter pain relievers.
• Clinically Proven Formula: A recent human clinical study tested Relieve-R against a leading over the counter pain relieve. Relieve-R was found to be a safe and effective alternative.
• Clinically Tested Ingredients: Relieve-R is formulated with all-natural, non-habit-forming ingredients, like L-Tetrahydropalmatine,  L-Theanine, White Willow, and Benfotiamine.
• Nature Works. Science Proves It: LifeSeasons creates natural, safe, and effective health supplements to help you feel your best. We utilize both the wisdom of nature and the progress of science in our targeted, high-quality formulas.

Life Seasons

• Sleep Aid: Allows you to fall asleep naturally and promotes a healthy sleep cycle, so you wake up feeling refreshed and not groggy
• Herbal Anti-Inflammatory: Soothing sleep supplement delivers herbs for healthy inflammation response to promote a restful night
• Drug-Free & Non-Habit Forming: Expertly formulated with potent, whole-food Valerian Root, Lemon Balm, Holy Basil & Turmeric
• No Black Pepper Needed: Unlike supplements formulated with isolated curcumin, New Chapter uses pure WHOLE Turmeric with 100s of compounds, including Curcumin and Turmerones for optimal absorption
• Non-GMO Project Verified, Certified Gluten Free by NSF, 100% Vegetarian, No Synthetic Fillers, No Artificial Flavors or Colors, FDA & GMP compliant, 3rd-party tested
• During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.

New Chapter

• Percogesic Backache Relief is a fast acting formula soothes your backaches away and available without prescription
• Magnesium salicylate, the key ingredient in Percogesic Backache Relief, is a nonsteroidal anti inflammatory drug (NSAID) that reduces back and muscular aches
• Effective analgesic with enhanced pain relief
• Easy to swallow coated tablets
• Pharmacist recommended

Percogesic

• PROMOTES MUSCLE RELAXATION: Do you frequently have aching back or neck pain when you feel stressed or overwhelmed? When you have stress in your life, your body may respond with muscle tension. It can even lead to involuntary tightness, hardness, or bulging in a muscle, otherwise known as muscle spasms. Luckily, Muscle Ezze Plus 24/7 is here to help! This revolutionary product works to help calm the body, therefore supporting muscle relaxation, which in turn helps to promote restful sleep.
• INGREDIENTS YOU CAN TRUST: Doctors Nutra provides you with beneficial ingredients that are naturally derived and gluten-free, ensuring safety. These ingredients include: magnesium, calcium, jujube, magnolia bark, ashwagandha, passion flower, lemon balm leaf, theanine, valerian root, and chamomile flower powder. This powerful blend of herbs, magnesium, and calcium works in cohesion to help reduce the negative effects of stress, as well as muscle cramps and spasms.
• FEEL CALM & REFRESHED: The calming effect of Muscle Ezze Plus 24/7, combined with a good night's sleep, helps to produce an overall sense of well-being and gives you the ability to face the next day with more calmness and energy. Getting a good amount of sleep is incredibly important for your health, as it helps your mind and body function properly, leading to increased energy. This is because while you’re asleep, your body is hard at work healing itself and optimizing different processes.
• EASY TO TAKE: Muscle Ezze Plus is easy to incorporate into your daily routine! During times of muscle discomfort or stress, we recommend to begin with 2 capsules up to 2 times daily. If you are taking it to help you sleep, take 4 capsules on an empty stomach with 8 ounces of water, 45-75 minutes before bed, or as directed by a health care professional. Due to the potency of this product, we recommend taking it in a safe and controlled environment.
• TRUST DOCTORS NUTRA: Doctors Nutra has dedicated itself for years to helping people like you reach their goals with their health and nutrition needs. We believe that nutrition plays a vital role in health and wellness. Using GMP and Organic manufacturing, Doctors Nutra sets high standards for purity and quality. Years of combined experience in the international sourcing of raw materials, allows Doctors Nutra to deliver consistent, high quality products

Doctors Nutra Nutraceuticals

• Dee Cee Laboratories Formula 303 Natural Relaxant, natural relief for muscle spasm, tension, and stress.
• Formula 303 is an all-natural herbal remedy that harnesses the medicinal properties of valerian root, passion flower, and magnesium to provide you with relaxed muscles, stress relief, and natural relief from muscle pain relief, joint pain relief, leg cramp relief, and stress relief.
• A perfectly formulated balance of Valerian Root, Passion Flower, and Magnesium for sore muscle relief and much more.
• Formula 303 is made from natural ingredients and may have a distinctive earthy odor, taste, and color of tablets may vary.
• Gluten Free, Non-GMO manufactured for almost 60 years in the USA, in an FDA registered and inspected facility in full compliance with current Good Manufacturing Processes.

Dee Cee Laboratories

• ✅ NON-DROWSY RELIEF FROM MUSCLE SPASMS AND CRAMPS: Mag 3D contains non-drowsy natural ingredients that actually boost energy levels by improving circulation, nerve health, and muscular function (cramp and pain relief without grogginess). Mag 3D is the only non-drowsy natural muscle relaxer on the market.
• ✅ THREE WAYS MAG 3D RELIEVES SPASMS, CRAMPS, ACHES & PAINS: (1) Supports total nerve health, (2) improves nutrient & blood circulation, and (3) prevents mineral deficiencies that lead to muscular & nerve dysfunction.
• ✅ ADDRESSES ALL THREE ROOT CAUSES of muscle spasms, cramps, pain and tension. Unlike other supplements or OTC products that address only symptoms, Mag 3D gets to the root of your cramps and pain.
• ✅ CLINICALLY-SUPPORTED NATURAL INGREDIENTS: Made in the USA in a GMP Approved Facility with clinically-supported, trademarked ingredients including Albion Magnesium Malate, Curcumin C3 Complex Turmeric Extract, and BioPerine Black Pepper Extract.
• ✅ SALTWRAP’S QUALITY GUARANTEE: Mag 3D is 100% GUARANTEED. If you don't love it after one dose, we'll refund your money. No questions asked (the seller of this item, SaltWrap, is solely responsible for all guarantees stated). We encourage you to use Mag 3D for a full 30 days to get the full benefit. But, you are welcome to request a refund anytime within 90 days of your purchase by contacting us directly.

SaltWrap

• Apply Penetrex to your Back, Neck, Knee, Hand, Foot, and more. Penetrex is recommended for use on its own and is also appropriate for use in conjunction with complementary therapies such as heating pads, ice packs, massagers, and supplements.
• Utilizing a revolutionary delivery system, Penetrex delivers unique ingredients including Arnica, Glucosamine, MSM (DMSO2), Choline, Boswellia Serrata & Vitamin B6 into the tissue to soothe affected areas.
• Your Penetrex purchase is backed by our happiness pledge. Try our products without worry because we’re confident that you will be thrilled with your purchase.
• Vanishing scent, non-greasy, non-staining, paraben-free, and never tested on animals.
• Penetrex does not simply provide cooling and warming ingredients found in other formulations. Instead, Penetrex delivers targeted soothing benefits directly to the affected area(s).

Penetrex