9 Best Mitochondria Support Supplement of December 2025

• ASSISTS THE FUNCTIONING OF MITOCHONDRIA: This supplement is ideal to boost mitochondrial energy levels and improve their performance, due to a high count of pyrroloquinoline quinone.
• GREATER ENERGY LEVELS: Mito Cell PQQ professional-grade supplements are formulated to boost energy levels at a cellular level, resulting in an overall improvement in mental and physical metabolism, and body immunity.
• SUPPORTS BRAIN HEALTH & COGNITIVE PERFORMANCE: The PQQ compound is known to positively impact cellular pathways and stimulate nerve growth in the brain. This may support enhanced memory, concentration, and focus.
• ACTS AS ANTIOXIDANTS: The capsules also act as antioxidants and promote healthy aging, cognitive, and heart functioning in the body by combating the elements causing oxidative stress.
• 100% VEGAN & GLUTEN-FREE: Mito Cell PQQ is vegan and gluten-free, making them beneficial for vegetarians. These tablets are free of milk, egg, fish, wheat, soy, and artificial preservatives.

Neuro biologix

• ✔ HIGHEST POTENCY – our CoQ10 is provided with a meaningful 300mg dose and is the trans isomeric form of CoQ10 produced through a natural fermentation process. Our purified Shilajit extract is a potent 50% Fulvic Acid. Also, a full 21mg of PQQ is part of this all-in-one mitochondrial booster formula. Ideally taken in combination with 500mg Acetyl L-Carnitine
• ✔ EFFECTIVE – Coenzyme Q10 optimizes mitochondrial function and protects them from free radical damage. PrimaVie Shilajit , a phyto-mineral pitch found in the Himalayas, stabilizes, revitalizes and preserves CoQ10 in its active form, boosting the levels of Co Q10 available. PQQ activates genes that may induce mitochondrial biogenesis - the formation of new mitochondria
• ✔ PURE – Swiss BioEnergetics MitoDefence capsules are manufactured using only the finest quality raw materials in their best grade and purest form so that we can guarantee you receive a consistently high-quality product. Utilising the latest research to bring you premium, balanced, scientifically validated formulations free from: ✘gluten, ✘wheat, ✘added sugar, ✘yeast, ✘additives, ✘artificial colourings. Suitable for Vegetarians and Vegans
• ✔ PEACE OF MIND – our nutritional food supplements, vitamins, multivitamins, herbals, cleansers, tablets, extracts, powders, caps, creams, teas and pills are manufactured with care exclusively in the USA to GMP code of practice in an FDA registered facility, so you are safeguarded by the highest standards in the world
• ✔ OUR GUARANTEE – we have a no questions asked, money back guarantee policy so you can improve your nutrition and health with no risk. Also, we invest in the finest ingredients built into cutting edge formulas with no fancy labels, bottles or superfluous brand advertising. This is our model for delivering you real value with exceptional quality

swiss bioenergetics

• Energy & Healthy Aging Support - Designed to help support optimal mitochondrial biogenesis, which is critical for the promotion of healthy aging, optimal energy production, and protection from reactive oxygen species (oxidative stress).*
• What is PQQ? Pyrroloquinoline quinone is an enzyme cofactor possessing antioxidative, neuroprotective, and cardioprotective properties that encourage mitochondrial biogenesis.*
• Rhodiola Rosea Adaptogen - Research shows that Rhodiola rosea is a powerful herb for enhancing mitochondrial energy production and helps defend against free radicals in the nervous system as well as the mitochondria.*
• Always Pure & Effective Products - This product is Non-GMO and contains No Gluten, Dairy, or Soy. Eco-conscious, tinted glass bottles offer a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.*
• Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

designs for health

• ProThera and Klaire Labs have unified under the Klaire Labs logo. This unification will be reflected in new packaging and a continuing commitment to the founding Klaire Labs principles of purity, potency, and performance.
• Focused support for mitochondrial energy production.*
• Lecithin is excluded from MitoThera capsules for improved tolerance by those who are sensitive to soy.
• Supplies key nutrients and energy substrates to protect against free radicals and assist mitochondria in performing their critical functions most efficiently.*
• Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and yeast. Contains no artificial colors, flavors, or preservatives.

Klaire Labs

• Mitochondrial Support; PQQ helps promote Mitochondria Energy Cofactor levels and efficiency
• Promote Energy Levels; By helping Mitochondria work more efficiently, PQQ helps promote overall energy levels
• Supports Healthy Sleep Quality; An 8 week study revealed PQQ may help support sleep quality by supporting healthy cortisol levels
• Vegan, Non Gmo, Gluten Free; Double Wood's PQQ is Vegan, Non Gmo, and Gluten Free
• Manufactured and Tested in the USA; Double Wood's PQQ capsules are manufactured and tested for microbes and heavy metals right here in the USA

Double Wood Supplements

• ENERGY, HEALTHY AGING AND MAINTAINING RESILIENCE: Unique formula designed to support healthy energy levels, organ function and a lift in overall well-being.
• MITOCHONDRIAL HEALTH SUPPORT: Delivers targeted CoQ10 antioxidant support to your mitochondria - the power plants of your cells - to help your organs perform at their best.
• BREAKTHROUGH WELLNESS TECHNOLOGY: MitoQ is absorbed by your mitochondria hundreds of times more effectively than regular CoQ10 supplements.
• CELL SUPPORT AND BUILD RESILIENCE: Helps to limit free radical damage at the source, supporting your cells and building resilience, by reducing the risk of oxidative stress.
• SCIENTIFIC DATA TO SUPPORT QUALITY & SAFETY: Where possible, our ingredients have been selected and formulated to provide the highest level of bio-availability/ absorption. Our ingredients and products are manufactured to Good Manufacturing Practice (GMP) standards.

MitoQ

• TARGETED ANTIOXIDANT SUPPORT TO THE MITOCHONDRIA: The mitochondria is where your energy is made; MitoQ delivers targeted CoQ10 antioxidants directly into the mitochondria to help your organs perform at their best and beyond. The level of CoQ10 produced inside our mitochondria naturally declines with age. Positively charged ions in MitoQ easily pass through the mitochondria membrane, which makes CoQ10 available to perform vital functions for your health, unlike any other cellular supplement.
• NEXT-GEN ANTIOXIDANT FOR VITALITY: MitoQ is better absorbed by your cell powerhouses than regular antioxidants. MitoQ is able to pass easily through the cell wall to distribute CoQ10 directly to the sources allowing MitoQ to deliver targeted support directly to your mitochondria cells. Our innovative and proven effective method of reducing free radical damage increases the intensity of our health benefits and allows you to see proven results, sooner.
• BOOST ORGAN PERFORMANCE AND DAILY ENERGY LEVELS: 90% of your body's energy comes from the mitochondria, yet every year mitochondria produce less energy due to natural aging. This is a result of free radicals present in the body during the energy process damaging the walls of the mitochondria, which causes the cell to operate less effectively. MitoQ helps to limit free radical damage at the source, supporting your cells and building resilience by reducing the risk of oxidative stress.
• UNPARALLELED BREAKTHROUGH CELLULAR SCIENCE: MitoQ relies on advanced, patented CoQ10 technology based on two decades of research and $60 million of investments. Our ingredients have been selected and formulated to provide the highest level of bioavailability and absorption on the market. Not only does MitoQ build up the mitochondria’s free radical defence, but it also works to prevent future damage of the cell membrane which significantly increases the cell’s resilience and health.
• TRUSTED BY PROFESSIONALS FOR ENDURANCE AND RECOVERY: MitoQ is a mitochondria supplement expertly trusted by professional athletes and medical specialists to deliver high quality cell support. Support your mental focus, healthy aging, and boosted energy levels with the supplements that are shown to deliver optimized organ support. MitoQ ingredients and products are manufactured to Good Manufacturing Practice (GMP) standards so you can have confidence in the supplements that you take.

MitoQ

• Feed Your Cell’s Powerhouse with Mitochondrial Support | Everyone knows mitochondria are the powerhouse of your cells. Well this nifty mitochondrial restore formula has the optimal doses of antioxidants, adaptogens, vitamins, and transporters to feed your mitochondria. This Next-level mitochondria supplement contains the optimal mixture of HIGHLY RESEARCHED ingredients that help restore energy, cognition, and mood (already within normal ranges). Perfect for mitochondria support.
• Feel Fantastic | Comprehensive mitochondria formula with HIGHLY RESEARCHED ingredients that help restore energy, support cognition, and uplift mood (already within normal ranges). With precise doses of the best antioxidants, adaptogens, coenzymes, vitamins, and transporters for mitochondria repair, you’ll feed your cells what they need to thrive, not just a cheap stimulant rush, but a true mitochondrial energy optimizer
• More Complete Than Before | New research suggests the generic mitochondrial catalysts like the combination of Q10 and an NADH Supplement (nicotinamide adenine dinucleotide) used in most pills provides little to no benefit for mitochondria energy. Unlike those generic formulas,this groundbreaking formula uniquely contains all 4 proven mitochondrial supplements (CoQ10, ALA, N-Acetyl L-Carnitine, BioPQQ) plus 8 support supplements. That’s 12 supplements proven to “recharge” your batteries.
• More Than a Quick Boost | Many customers report a quick boost of energy to help in the gym, office, or home, but our formula goes much deeper than just fast energy. The high-potency, all-natural mix supports mitochondrial repair and function to restore youthful levels of energy. Instead of a quick, unsustainable boost, Mitrotrax wills your system to function at its peak, delivering clean, long-term energy.
• Safe. Easy. Effective | 100% Money-Back Guarantee | Mitrotrax is a balanced, cell-supporting diet in every capsule. An easy addition to any morning routine. Just 2 easy-to-swallow capsules is all you need to promote healthy cell function and give yourself the energy you need to conquer the day. Try it risk free. If you don’t feel the same clean, all-natural energy that so many of our customers (and we ourselves) feel each day, we will refund 100% of your money.

VitaMonk

• Most energy supplements use weak formulas with synthetic vitamins as fillers with unwanted side effects. With Peak Performance you can rest assured knowing that you’re getting the ingredients designed to give you good absorption and bioavailability.
• Your body's energy is generated by tiny cellular "power plants" called mitochondria. The problem is, as we age, our mitochondria often begin to malfunction and die off. And factors like stress and poor nutrition only deplete them even further. Supports mitochondrial health and efficiency to help the power plants in your cells create energy.*
• Enhanced with PQQ and CoQ10 - Works at a cellular level by pairing two natural ingredients: PQQ and CoQ10, giving this supplement the remarkable ability to support the healthy functioning of mitochondria. Both CoQ10 and PQQ occur naturally in the body, and are integral to good mitochondrial function and cellular energy production.*
• Most Supplements Sold Online Are Not 3rd Party Tested! This is a dirty secret that many supplement sellers don't want you to know that their products are Not independently 3rd party tested outside of their own facilities. Why? Because it's an extra out of pocket expense to conduct 3rd party testing and most companies will not sacrifice their profit. But Not Us. Peak Performance is committed to the Highest Standards for your safety.
• Over 400,000 Happy Customers + 1-for-1 Donation To Vitamin Angels. Peak Performance is celebrating over 400,000 happy customers and we are also very proud of our 1-for-1 donation match program. For every unit you purchase, through our partnership with the nonprofit Vitamin Angels, we will supply a child at risk of malnutrition with vitamins for 1 year! To date, we've supplied over 1 Million children with life changing Vitamins- So thank you for helping us continue this great cause!

Peak Performance Coffee