10 Best Toothpaste For Canker Sores of December 2025
List of Top Rated Toothpaste For Canker Sores from thousands of customer reviews & feedback.
Updated On Dec 2025
1,645 Reviews Studied
1
CloSYS Fluoride Toothpaste, 7 Ounce, Gentle Mint, Whitening, Sulfate Free Read Review
- Contains 1 - 7oz CloSYS Gentle Mint Flouride Toothpaste
- Results without abrasive ingredients- CloSYS Toothpaste does not contain Sodium Lauryl Sulfate (SLS) which has been linked to canker sores. Antimicrobial.
- Enamel protection – Fluoride provides exceptional enamel protection and fights cavities better than leading brands
- Ideal for sensitive mouths– naturally activated & pH balanced so it's gentle enough for sensitive mouths.
- Bright, white smile – CloSYS Sensitive Fluoride toothpaste gently removes stains with proper brushing.
- Fresh & clean without pain & irritation– Gentle Mint flavored toothpaste kills germs and fights plaque for a noticeably cleaner, brighter and fresher mouth for hours.
2
Squigle Enamel Saver Toothpaste (Canker Sore Prevention & Treatment) Prevents Cavities, Perioral Dermatitis, Bad Breath,... Read Review
- This No SLS formula is ideal for Canker Sore sufferers
- No artificial colors, preservatives, colors, sweeteners
- 36% Xylitol - made from birch and beech trees
- Contains Fluoride
- Each Tube is 4.0 oz
3
Squigle Tooth Builder SLS Free Toothpaste (Stops Tooth Sensitivity) Prevents Canker Sores, Cavities, Perioral Dermatitis... Read Review
- Fluoride Free and SLS (Sodium Lauryl Sulfate) Free
- Contains 36% Xylitol - Profoundly inhibits plaque
- Nanosized Calcite - Seals exposed dentin, replaces lost calcium and neutralizes acids
- Unflavored Toothpaste
- Made in the USA
4
Verve Ultra SLS-Free Toothpaste with Fluoride, 4.5 oz. (Pack of 4) Read Review
- SLS Free Toothpaste, non-irritating formula
- Fluoride to prevent cavities
- Soothing fresh mint taste
- Effective stain removal
- Vitamin E enriched, contains no animal products, Made in USA
5
Squigle Enamel Saver Toothpaste (Canker Sore Prevention & Treatment) Prevents Cavities, Perioral Dermatitis, Bad Breath,... Read Review
- Squigle contains no sodium lauryl sulfate so it is ideal for Canker Sore sufferers
- Helps prevent Canker Sores, Dry Mouth, Mouth Ulcers, Perioral Dermatitis
- SQUIGLE has 36% by weight of Xylitol (Made from birch and beech trees). The more Xylitol in your toothpaste, the less plaque buildup in your mouth. Plaque is an irritant that triggers canker sores.
- Very mild peppermint flavor with no artificial colors, preservatives, colors, sweeteners
- Contains Fluoride
6
Squigle Tooth Builder SLS Free Toothpaste (Stops Tooth Sensitivity) Prevents Canker Sores, Cavities, Perioral Dermatitis... Read Review
- Nanosized Calcite - Seals exposed dentin, replaces lost calcium and neutralizes acids.
- Contains 36% Xylitol - Profoundly inhibits plaque
- Fluoride Free and SLS (Sodium Lauryl Sulfate) Free.
- No added flavor or unpleasant toothpaste taste.
- Made in the USA
7
Verve Ultra SLS-Free Toothpaste with Fluoride, 4.5 oz. Read Review
- SLS Free Toothpaste, non-irritating formula
- Fluoride to prevent cavities
- Soothing fresh mint taste
- Effective stain removal
- Vitamin E enriched, contains no animal products, Made in USA
8
Squigle Enamel Saver Toothpaste (Canker Sore Prevention & Treatment) Prevents Cavities, Perioral Dermatitis, Bad Breath,... Read Review
- Squigle contains no sodium lauryl sulfate so it is ideal for Canker Sore sufferers
- Helps prevent Canker Sores, Dry Mouth, Mouth Ulcers, Perioral Dermatitis
- SQUIGLE has 36% by weight of Xylitol (Made from birch and beech trees). The more Xylitol in your toothpaste, the less plaque buildup in your mouth. Plaque is an irritant that triggers canker sores.
- Very mild peppermint flavor with no artificial colors, preservatives, colors, sweeteners
- Contains Fluoride
9
Squigle Enamel Saver Toothpaste (Canker Sore Prevention & Treatment) Prevents Cavities, Perioral Dermatitis, Bad Breath,... Read Review
- Squigle contains no sodium lauryl sulfate so it is ideal for Canker Sore sufferers
- Helps prevent Canker Sores, Dry Mouth, Mouth Ulcers, Perioral Dermatitis
- SQUIGLE has 36% by weight of Xylitol (Made from birch and beech trees). The more Xylitol in your toothpaste, the less plaque buildup in your mouth. Plaque is an irritant that triggers canker sores. A leading canker sore toothpaste has only 10% Xylitol.
- Very mild peppermint flavor with no artificial colors, preservatives, colors, sweeteners
- Contains Fluoride
10
Squigle Enamel Saver Toothpaste (Canker Sore Prevention & Treatment) Prevents Cavities, Perioral Dermatitis, Bad Breath,... Read Review
- Squigle contains no sodium lauryl sulfate so it is ideal for Canker Sore sufferers
- Helps prevent Canker Sores, Dry Mouth, Mouth Ulcers, Perioral Dermatitis
- SQUIGLE has 36% by weight of Xylitol (Made from birch and beech trees). The more Xylitol in your toothpaste, the less plaque buildup in your mouth. Plaque is an irritant that triggers canker sores.
- Very mild peppermint flavor with no artificial colors, preservatives, colors, sweeteners
- Contains Fluoride