9 Best Hot Spot Spray For Dogs of December 2025

• #1 PET GROOMING BRAND IN THE USA*—Join the millions of pet parents who can’t get enough of Burt’s Bees for Pets by using America’s #1 pet grooming brand
• CALMS AND SOOTHES — This hot spot spray gets the job done when it comes to calming and soothing irritated skin and hot spots
• MADE WITH CHAMOMILE AND ROSEMARY — Soothing chamomile and rosemary team up to naturally nourish the skin and reduce irritation
• FOR ALL DOGS — This hot spot spray is suitable for all dogs no matter the size or breed Take care of your pup's hot spots today
• 100% SAFE — Vet recommended formula is pH balanced for dogs colorant free sulfate free cruelty free and made with no added fragrances in the USA

Burt's Bees

• ADVANCED SOLUTION FOR BETTER WOUND CARE: Keep Maxi Wash on hand for all your pet's first aid and skin care needs. We utilize unique technology to power Maxi Wash for the best way to clean cuts, scrapes, promote healing of wounds, sores, rashes, and other skin irritations.
• PROMOTES HEALING: Maxi Wash effectively cleans wounds and creates an optimal environment for ultimate healing for a majority of wounds and helps prevent and resolve various infections.
• COMPLETELY SAFE AND NON-TOXIC: Maxi Wash is a safer alternative to antibiotics and steroids for proper wound management. The non-toxic pH-balanced formula is safe for the entire family, from newborns to elderly adults, and is safe enough to use around sensitive areas ears, nose, and mouth.
• NON-STINGING WOUND CLEANSER: Contrary to popular belief, your wound cleanser doesn’t need to sting or burn in order for it to work. Maxi Wash has no alcohol, iodine, or any other ingredients that would cause stinging or irritation during application.
• CLINICALLY PROVEN AND VETERINARIAN RECOMMENDED: Maxi Wash uses similar active ingredients to what is currently being used in many veterinary clinics and animal hospitals around the world to help clean and manage wounds and skin problems. This product is FDA Registered Over-the-Counter (OTC) Animal Drug. NDC: 72127-0704-0

Forticept

• Helps Relieve Skin Infections Like Hot Spots, Growths, & Acne In Pets. Helps Heal Skin Infections, Superficial Cuts, Abrasions & Insect Bites.
• Non Stinging Solution For The Topical Management Of Skin Problems. deodorizes And Helps Relieve Dermatitis And Pyoderma Which Can Result From Allergies.
• Perfect Between Baths and Easier Than Shampoos . Useful for the Medicated Cleansing of Face Folds, Finger Folds, as Well as Underarm and Groin. Astringent Qualities Also Help to Dry the Affected Area.
• Helps Eliminate Both of the Causes Most Commonly Associated with Skin Infections in Dogs and Cats.
• Made in the USA in Federally Regulated Manufacturing Facilities to Ensure Quality and Safety.

Pet MD

• 🐾 RELIEF FOR ITCHY AND IRRITATED SKIN: Medicated spray to provide relief from itching and irritation caused by hot spots and allergies.
• 🐾 MOISTURIZING RELIEF: Moisturizing formula helps give relief to dogs with hot spots, scrapes, and abrasions.
• 🐾 EASY TO USE: Spray application allows you to easily treat affected areas.
• 🐾 TRUSTED BRAND: Try our entire line of products dedicated to keeping your best friend happy and healthy.

Sulfodene

• IMMEDIATE RELIEF - Vet’s Best Hot Spot Spray for Dogs provides immediate relief for itchy, dry, and irritated dog skin on contact, helping to soothe hot spots and seasonal skin irritation.
• PLANT-BASED INGREDIENTS - A unique blend of natural key ingredients, including tea tree oil, aloe vera, and chamomile, provides fast and effective relief.
• NO-STING FORMULA - Our alcohol-free, no-sting formula provides soothing relief for red, raw, or inflamed skin. Does not contain steroids such as hydrocortisone.
• IT WORKS - Guaranteed effective and will not affect topical flea and tick control products.
• VET’S FORMULA - Veterinarian formulated and recommended, and made in the USA with quality US and imported ingredients.

Vet's Best

• No.1 PET GROOMING BRAND IN THE USA*—Join the millions of pet parents who can’t get enough of Burt’s Bees for Pets by using America’s No.1 pet grooming brand
• CALMS AND SOOTHES — Burt's Bees hot spot spray soothes your dog's itchy and irritated skin to keep them from biting, itching, and scratching
• MADE WITH THE HIGHEST QUALITY INGREDIENTS — All natural ingredients include aloe vera, which moisturizes skin and apple cider vinegar, which naturally restores pH balance and eases hot spot irritation
• SUITABLE FOR ALL DOGS AND PUPPIES — This mild dog hot spot spray is specifically pH balanced for all dogs and puppies
• 100% SAFE — The sulfate-free veterinarian recommended formula of this dog hot spot spray is free of fragrances, colorants, and harsh chemicals

Burt's Bees

• Helps with your dog or cat's dermatitis, hot spots, rashes, and more
• Provides relief for symptoms of allergies, such as dry, sensitive or itch skin
• Promotes healing process by keeping sore clean and moist
• No stinging or irritation with application
• Completely safe and non-toxic - can be used on all animal species and is safe if licked or ingested
• Veterinary-recommended for every pet parent to keep on hand for all of your pet’s hot spot and skin care needs

Vetericyn

• Helps Relieve Skin Infections, Hot Spots, Paw Licking, Allergies, Growths & Acne in Dogs, Puppies, Cats, Kittens and Horses
• No Sting Alcohol-Free Formula Relieves Itching and Hot Spots; Aloe & Vitamin E soothes and nourishes Rashes, Redness and Dry Skin Irritations
• Perfect between Baths and Easier that Shampooing. Deodorizes and Cleanses Face Folds, Wrinkles, Paws, Underarms and Groin Leaving a Pleasant Cucumber Melon Scent
• Veterinary Strength Medicated Formula is for Dogs, Cats and Horses
• Made in the USA in Federally Regulated Manufacturing Facility in Small Batches for Quality and Safety

BEXLEY LABS

• HEAL & SOOTHE – Veterinary Formula Clinical Care Hot Spot and Itch Relief Spray provides dogs and cats with medicated analgesic and anti-inflammatory relief of itchy skin and hot spots commonly caused by allergies, insect bites, matted dirty coats & more
• FAST ACTING – This itch relief spray works fast to help relieve your pet’s symptoms including biting, licking, scratching, and swollen, pink-to-red, warm-to-hot, moist-to-wet, irritated-to-bloody issues associated with skin irritations
• VETERINARY RECOMMENDED – This anti-itch spray for dogs and cats is paraben & dye-free. It will not remove topical spot-on flea and tick treatments. Lidocaine and Hydrocortisone reduce itching, redness and swelling while Allantoin stimulates wound healing
• FOR DOGS AND CATS – This pet hot spot treatment is for topical use on both dogs and cats over 12 weeks of age. It has a pleasant smell and does not burn when applied
• EFFECTIVE & AFFORDABLE – Veterinary Formula Clinical Care premium medicated products are created with veterinary-grade ingredients, available at an affordable price. We know dogs and cats are more than just pets because we are pet parents too
• Age range description: all life stages
• APPLICATION: This product is intended for use as a topical application for hot spots. Read directions carefully before using. Test on a small area prior to first use

Veterinary Formula