10 Best Glucose Metabolic Support of December 2025

• In the United States 86 million people (approximatly 37% of the US population) have prediabetes which may evolve into T2D during their lifetimes if left untreated. Metabolic syndrome (MetS) is also considered a prediabetes equivalent.
• Prediabetes is a condition where blood sugar levels are higher than normal and, if left untreated, can result in type 2 diabetes (T2D). Prediabetes is defined by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT), two conditions where the blood sugar levels have not yet reached the treshold for T2D's onset.
• What is PreDia - a new and revolutionary dietary supplement for people who have prediabetes & metabolic syndrome. Often diet and exercise is needed to combat these conditions. Now, PreDia is also there to help when you need it most. Powered by GSECM-50 a source of the scientifically proven dosage of abscisic acid (ABA) made of Grape seed extract, chromium and magnesium. PreDia has been shown to improve the typical markers associated with both prediabetes and metabolic syndrome when combined
• PreDia works by controlling glycemia either by delaying or reverting the onset of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) which are tipically associated with the prediabetic condition. PreDia's main function revolves around Abscisic acid (ABA) contained in its Grape Seed extract ingredient. Our unique and patented dosage of ABA significantly reduces fasting glycemia and glycated hemoglobin and also the glycemic profile after a meal.
• PreDia exerts its action on glycemic control not by increasing but by reducing insulin secretion required to lower glycemia after carbohydrates intake. Studies have shown that the dose of ABA contained in PreDia can replace the insulin action by stimulating, in an insulin-independent manner,the skeletal muscle glucose uptake. The capability of saving insulin secretion to control glycemia represents the most important mode of action of PreDia.

WynnPharm

• Promoting healthy glucose metabolism
• Supporting healthy insulin function
• Providing plant-based ingredients that may promote antioxidant activity
• Indications for use: Horses struggling with excess weight or fat deposits, especially on the rump or neck, Horses who exhibit seasonal pasture sensitivities, Horses struggling with changing insulin levels
• Standard Process: High-quality products that work the way nature intended

Standard Process Inc.

• BLOOD SUGAR AND INSULIN LEVELS SUPPORT: Unique formula designed to support blood sugar and insulin levels within the normal limits, optimize weight management and key organ health.
• WORLD FIRST: Only product in the world to combine super antioxidant MitoQ with Chromium, Cinnamon and Zinc to support natural sugar metabolism and weight management.
• ADVANCED AND PATENTED Q10 ANTIOXIDANT TECHNOLOGY: Delivers targeted CoQ10 antioxidant support to your mitochondria - the power plants of your cells - to help your organs perform at their best. MitoQ is absorbed by your mitochondria hundreds of times more effectively than regular CoQ10 supplements.
• CELL SUPPORT AND BUILD RESILIENCE: Helps to limit free radical damage at the source, helping to support your cells and build resilience, by reducing the risk of oxidative stress.
• SCIENTIFIC DATA TO SUPPORT QUALITY & SAFETY: Where possible, our ingredients have been selected and formulated to provide the highest level of bio-availability/ absorption. Our ingredients and products are manufactured to Good Manufacturing Practice (GMP) standards.

MitoQ

• Developed to support a healthy weight and appetite for your pup.
• VETERINARIAN RECOMMENDED: NOW Pet Glucose Metabolic Support is a health supplement formulated by renowned veterinarian Dr. Barbara Royal, DVM, CVA, founder of The Royal Treatment Veterinary Center.
• NASC CERTIFIED: NOW Pets has been certified by the National Animal Supplement Council (NASC), an organization that protects and enhances the integrity of the animal health product industry by promoting the well-being of non-human food chain animals that are given animal health supplements by their owners.
• NOW Pets premium pet supplements are formulated and manufactured with the same attention to quality and detail NOW puts into their supplements intended for humans, from the sourcing of top-quality ingredients to finished product testing.
• Packaged in the USA by a family owned and operated company since 1968.

NOW

• 🥑 SUPPORT METABOLISM: Combined with a healthy diet, these natural plant-based bioactive AvoB and chromium vegan capsules help boost your metabolism and curb cravings, aiding in fat and weight management, all while helping with chromium deficiency so that your body can better support glucose levels. Great for women and men
• 🥑 EVERYDAY USE: Easy to swallow vegan capsules deliver a standardized dose of medicinal grade, non-GMO, bioactive AvoB derived from all natural dried avocados. This supplement helps support blood health and boost body's ability to metabolize nutrients. Each bottle contains a 30 day supply. Take 4 capsules once daily or 2 capsules twice daily.
• 🥑 VEGAN AND KETO DIET FRIENDLY: Support your Vegan and KETO diet with one of nature's superfoods. Made with high quality freeze dried avocados, each serving is packed with superfood qualities of avocado including bioactive AvoB, antioxidants, carotenoids, vitamin E and fiber.
• 🥑 OVER 8 YEARS OF RESEARCH: Nutritional scientists at the University of Guelph took 8 years to identify this powerful bioactive. Preclinical studies show that starting at 30 days of consistent use, AvoB helped reverse insulin resistance, and had positive metabolic effects.
• 🥑 US 100% SATISFACTION GUARANTEE: Proudly manufactured in an FDA registered, inspected, and GMP-certified facility.

Metavo

• Supports healthy metabolic function - Drug-free formula supports metabolic function & glucose utilization.*
• Promotes healthy carbohydrate and lipid metabolism - Formulated to help regulate absorption and metabolism of dietary carbohydrates and lipids.*
• Maintains balanced insulin response & signaling - Olive leaf extract and chromium support insulin sensitivity and signaling response. Berberine and alpha lipoic acid may also help to regulate lipid metabolism.*
• Supports healthy weight & lifestyle - Insulin Health's natural formulation of herbs & minerals helps support a healthy weight and active lifestyle.*
• Zero chemicals, zero artificial additives - Every single LES Labs dietary supplement is manufactured in the USA in our state-of-the-art GMP-certified facilities. Order your LES Labs drug-free insulin health support caps with confidence.

LES Labs

• Carbohydrate Metabolism Support: Designed to provide essential nutrients to support pancreas function and healthy carbohydrate metabolism.*
• Metabolic Support: Carbohydrate Support Formula also supports healthy carbohydrate utilization as well as fat metabolism.*
• Antioxidant Support: Alpha lipoic acid is a versatile nutrient that provides antioxidant activity and supports healthy carbohydrate metabolism.*
• Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
• Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

Pure Encapsulations

• A premium probiotic supplement. Our Glucose Support Probiotic is uniquely designed to contain 7 Targeted Probiotic Strains, Banaba Leaf Extract, and Vitamin D3 to help support digestive, metabolic, and immune health.
• A simple and convenient delivery method. Just take 1 tablet per day with or without food. There are 60 tablets per bottle making this roughly a 2 month supply! This product is vegetarian, is gluten free and has zero sugar.
• Get 15 times more survivability with these tablets than with standard vegetarian capsules. the probiotic organisms in this formula are released over an 8-10 hour period so they bypass your stomach acids and reach deep into your intestinal tract alive (where they are needed most) so you can experience the benefits that probiotics have to offer.
• Tested for safety the highest quality possible. At Hyperbiotics, we love making a difference by leveraging the latest research to develop premium probiotic formulas and empowering individuals on their journey toward greater health. Our ingredients are carefully selected and follow good manufacturing practices when producing and packing each batch.
• Manufactured in the USA! Our probiotics are manufactured in Washington and Colorado in facilities that are GMP certified through NSF. We adhere to the strictest quality control and FDA guidelines and perform rigorous testing on every lot to ensure they are survivable and as the label states.

Hyperbiotics

• Supports Glucose Metabolism: Glucose Optimizer is a unique blend of vitamins, minerals, and botanicals that support glucose metabolism and antioxidant status
• Blood Glucose and Energy Metabolism: The formula contains alpha lipoic acid to support blood glucose and energy metabolism; Plus, it includes resveratrol for cardiovascular health, and magnesium for glucose metabolism and energy production
• Herbal Extracts for Glucose Metabolism: Banaba, gymnema, bitter melon and eucalyptus are herbal extracts supporting glucose metabolism; Glycostat Wild Bitter Melon Extract, produced from a wild genotype, supports blood glucose metabolism and transport
• Suggested Use: Take two tablets twice per day with meals or as directed by your qualified healthcare professional; This formula is suitable for vegetarians and vegans
• Superior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency

Jarrow Formulas

• 2 pack
• Superior Formula with GlucoFit
• Supports Glucose Metabolism
• Minimizes Sweet Cravings*

Now Foods