10 Best Fluoride Toothpaste of December 2025

3M Medical

• WHAT YOU'LL GET: Three 4-ounce tubes of Tom's of Maine Whole Care Toothpaste in Spearmint Flavor
• CAVITY PROTECTION: Fights cavities while freshening breath and preventing tartar buildup
• WHITENING TOOTHPASTE: Naturally derived silicas help remove surface stains for a brighter smile
• STRENGTHENS TEETH: Fluoride toothpaste promotes remineralization to strengthen enamel
• NATURAL & RESPONSIBLE: Contains no artificial sweeteners, preservatives, colors or flavors and is not tested on animals

Tom's of Maine

• NU SKIN AP 24 Whitening Fluoride Toothpaste lightens teeth without peroxide while preventing cavities and plaque formation. This gentle, vanilla mint formula freshens breath and provides a clean, just-brushed feeling that lasts all day.

Nu Skin

• Use Crest Gum Detoxify Deep Clean Toothpaste for clinically proven healthier gums
• Neutralizes plaque bacteria, even around the gum line to fight gingivitis
• Activated foam seeks out plaque bacteria in hard to reach places
• Gently cools gums during and after brushing

Crest

• Three 4 oz tubes of Alpine Breeze flavored Sensodyne Pronamel Gentle Teeth Whitening Enamel Toothpaste for Sensitive Teeth, to Reharden and Strengthen Enamel
• Acid erosion toothpaste that delivers minerals into the enamel layer to protect your teeth from acid erosion caused by acidic foods and drinks
• Sensitivity toothpaste that protects your teeth from pain triggers like temperature changes, acids, sweets or contact
• Strong enamel toothpaste that offers effective protection against cavities and improves your overall tooth enamel health
• Sensitive enamel toothpaste specially formulated to gently polish away stains, restoring the natural whiteness of your teeth
• Refreshing Alpine Breeze sensitivity toothpaste for clean teeth and fresh breath
• Brush for two minutes, twice daily

PRONAMEL

• MINT TOOTHPASTE: Mild mint toothpaste with exciting foaming action that helps clean those hard-to-reach places.
• ADA ACCEPTED: Our dentist recommended toothpaste is accepted by the American Dental Association.
• HYGIENE BENEFITS: Fluoride toothpaste prevents cavities, gingivitis, plaque and is triclosan free.
• RECOMMENDED AGES: Professional tooth paste is for children and adults 2-years of age and older.
• 3-PACK: With our best toothpaste, you will receive three 4.0oz tubes of mint toothpaste.

PRO-SYS

• WHAT YOU'LL GET: Three 5.1-ounce tubes of Tom's of Maine kids fluoride toothpaste in Silly Strawberry Flavor
• ADA APPROVED: Contains fluoride for anticavity protection, and calcium and silica to gently clean teeth
• TASTE THEY LOVE: This natural kids toothpaste comes in a fun, fruity flavor to help develop brushing habits
• RECYCLABLE TUBE: Once empty, replace cap and recycle with #2 plastics
• NATURAL & RESPONSIBLE: Contains no artificial preservatives, colors or flavors and is not tested on animals

Tom's of Maine

• Fluoride toothpaste fights and protects against cavities for healthier teeth
• Clinically proven to strengthen teeth enamel and cleans teeth thoroughly
• Anti-cavity toothpaste with a great mint taste leaves mouth feeling fresh and clean; the mint ingredient is sourced from American mint farmers
• American Dental Association (ADA) accepted and trusted by dentists for over 45 years
• Gluten free toothpaste formula
• Pack of 6 toothpaste tubes with 6 ounces in each; A total of 36 ounces

Colgate

• WHAT YOU'LL GET: Two 4.7-ounce tubes of Tom's of Maine Wicked Fresh! Natural Toothpaste with Fluoride in Cool Peppermint Flavor
• FRESHENS BREATH: Licorice root extract helps block bad breath germs for fresh breath
• CAVITY PROTECTION: Fluoride toothpaste cleans and strengthens teeth to promote a healthier mouth
• SMILE WITH TOM'S: Clinically proven to freshen breath and fight cavities
• NATURAL & RESPONSIBLE: Contains no artificial sweeteners, preservatives, colors or flavors and is not tested on animals

Tom's of Maine

• Biotene Fluoride Toothpaste Fresh Mint Original is specially formulated to not irritate a Dry Mouth
• Uses fluoride to help strengthen and protect teeth against cavities
• Offers an alcohol-free, sugar free and SLS free formula
• Freshens breath
• Number 1 Dentist Recommended Dry Mouth brand (Quintiles IMS, data through 4/30/2018)

biotène