10 Digestive Enzymes Supplements in 2026
List of Top Rated Best Digestive Enzymes Supplements from thousands of customer reviews & feedback.
Updated On Feb 2026
462 Reviews Studied
- Supports gut lining and digestive health
- Free-form amino acids for better absorption
- Helps reduce bloating and digestive stress
- Sugar-free, gluten-free, and non-GMO
- Suitable for sensitive stomachs
★ Popular Choice
- Contains a comprehensive blend of plant-based enzymes to support the digestion of a wide range of foods, including proteins, carbs, fats, and fiber.
- Includes prebiotics and probiotics to further support gut health and promote a balanced microbiome for optimal digestion.
- Helps to relieve occasional gas, bloating, and indigestion, allowing you to enjoy your favorite foods without discomfort.
- Features a veggie capsule that is suitable for vegetarians and vegans, catering to various dietary preferences and needs.
- Undergoes rigorous third-party testing to ensure purity, potency, and safety, providing peace of mind about the quality of the product.
- Offers a broad spectrum of digestive enzymes, including amylase, protease, lipase, cellulase, and lactase, to break down a wide variety of foods.
- Contains betaine hydrochloride (HCl) to support stomach acid production, which is crucial for protein digestion and nutrient absorption.
- Helps to improve nutrient absorption by breaking down food into smaller, more easily absorbed molecules, maximizing the benefits of your diet.
- Reduces occasional gas, bloating, and indigestion, promoting a more comfortable and enjoyable eating experience.
- Formulated with a focus on purity and potency, ensuring that you're getting a high-quality product that delivers consistent results.
- Features a proprietary blend of enzymes designed to support optimal digestion and nutrient absorption, maximizing the benefits of your food intake.
- Includes a focus on enzymes that break down complex carbohydrates and plant fibers, reducing gas and bloating associated with these foods.
- Provides support for individuals with sensitivities to certain foods, such as gluten and dairy, by aiding in the breakdown of these potentially problematic substances.
- Formulated with high-quality ingredients and undergoes rigorous testing to ensure purity, potency, and safety, meeting Dr. Mercola's stringent standards.
- Delivers enzymes in a delayed-release capsule to protect them from stomach acid and ensure they reach the small intestine where they are most effective.
- Offers a cost-effective way to support digestion with a blend of enzymes, including betaine HCl, ox bile extract, and pancreatin, to aid in the breakdown of proteins, fats, and carbohydrates.
- Contains ox bile extract to support fat digestion and absorption, which is particularly helpful for individuals with gallbladder issues.
- Helps to reduce occasional gas, bloating, and indigestion, allowing you to enjoy your meals without discomfort.
- Provides a comprehensive enzyme blend at an affordable price point, making it accessible to a wide range of consumers.
- Formulated with quality ingredients and undergoes testing to ensure purity and potency, meeting NOW Foods' rigorous standards.
- Formulated with a blend of enzymes specifically chosen to target the causes of bloating, including enzymes that break down complex carbohydrates and plant fibers.
- Contains ginger and peppermint to soothe the digestive tract and reduce inflammation, further alleviating bloating and discomfort.
- Helps to improve nutrient absorption by breaking down food into smaller, more easily absorbed molecules, maximizing the benefits of your diet.
- Reduces occasional gas, bloating, and indigestion, promoting a more comfortable and enjoyable eating experience.
- Formulated with quality ingredients and undergoes testing to ensure purity and potency, meeting United Naturals' rigorous standards.
- Features a high-potency blend of enzymes, including amylase, protease, lipase, cellulase, and lactase, to provide comprehensive digestive support.
- Contains ATPro, an exclusive blend of ATP, magnesium, phytase, and CoQ10, to further enhance enzyme activity and promote nutrient absorption.
- Helps to reduce occasional gas, bloating, and indigestion, allowing you to enjoy your meals without discomfort.
- Supports the digestion of a wide range of foods, including proteins, carbs, fats, and fiber, making it suitable for various dietary needs.
- Formulated with high-quality ingredients and undergoes rigorous testing to ensure purity, potency, and safety, meeting Enzymedica's stringent standards.
- Formulated without common allergens, including gluten, dairy, soy, nuts, and artificial additives, making it suitable for individuals with sensitivities and allergies.
- Contains a broad spectrum of digestive enzymes, including amylase, protease, lipase, cellulase, and lactase, to break down a wide variety of foods.
- Helps to improve nutrient absorption by breaking down food into smaller, more easily absorbed molecules, maximizing the benefits of your diet.
- Reduces occasional gas, bloating, and indigestion, promoting a more comfortable and enjoyable eating experience.
- Undergoes rigorous testing to ensure purity and potency, meeting Pure Encapsulations' stringent standards for hypoallergenic supplements.
- Contains a multi-enzyme complex consisting of amylase, protease, cellulase, lactase, and lipase, to support the digestion of a wide variety of foods.
- Helps to improve nutrient absorption by breaking down food into smaller, more easily absorbed molecules, maximizing the benefits of your diet.
- Reduces occasional gas, bloating, and indigestion, promoting a more comfortable and enjoyable eating experience.
- Offers a consistent and reliable source of digestive enzymes, ensuring that you're getting a quality product that delivers results.
- Formulated with quality ingredients and undergoes testing to ensure purity and potency, meeting Healthy Origins' rigorous standards.
Introduction
Let's face it: no one enjoys talking about digestive problems. Bloating, gas, indigestion – these are the silent struggles many of us endure. But what if I told you that the solution could be as simple as adding a digestive enzyme supplement to your daily routine? These little powerhouses can make a significant difference in how your body processes food, impacting everything from nutrient absorption to overall energy levels. We've sifted through the noise to bring you the top contenders for 2026.
What Are Digestive Enzymes?
Digestive enzymes are proteins that act as catalysts in your body, speeding up the breakdown of food into smaller, more easily absorbed molecules. Your body naturally produces these enzymes in the pancreas, stomach, and small intestine. However, factors like age, diet, and certain medical conditions can lead to enzyme deficiencies. This is where digestive enzyme supplements come in, providing an extra boost to support healthy digestion. They target different macronutrients: amylase breaks down carbohydrates, protease handles proteins, and lipase tackles fats. Some supplements even include enzymes to digest fiber and lactose.
How To Choose The Best Digestive Enzyme Supplement
Choosing the right digestive enzyme supplement requires careful consideration. First, identify your specific digestive issues. Do you struggle with lactose intolerance? Look for a supplement with lactase. Have trouble digesting fats? Lipase should be a priority. Next, consider the source of the enzymes. Plant-based enzymes are generally considered vegan-friendly and can be effective across a wider pH range. Also, pay attention to the potency of the enzymes, measured in activity units like HUT (for protease) and LU (for lipase). Finally, read reviews and look for supplements from reputable brands that conduct third-party testing to ensure quality and purity. Don't be afraid to experiment to find what works best for your individual needs – it may take some trial and error.
Top 10 Digestive Enzymes Supplements Reviews
Here's a quick rundown of our top picks for digestive enzyme supplements in 2026:
- Zenwise Digestive Enzymes: Best Overall
- Source Naturals Daily Digestive Enzymes: Best Broad-Spectrum
- Dr. Mercola Digestive Enzymes: Premium Quality
- NOW Super Enzymes: Budget-Friendly
- Garden of Life Raw Enzymes: Vegan Choice
- United Naturals Digest Complete: For Bloating
- Enzymedica Digest Gold: Powerful Formula
- Pure Encapsulations Digestive Enzymes Ultra: Hypoallergenic Option
- Nature's Sunshine Proactazyme: Targeted Relief
- Healthy Origins DigeZyme: Consistent Performance
Now, let's dive into the details of each supplement and explore what makes them stand out.
