10 Best Denture Cleaner of December 2025

• Effervescent 5-in-1 cleansing system; actively cleans, whitens and freshens retainers, dentures and other dental appliances
• Kills 99.9% of odor-causing bacteria
• Effectively removes stubborn stains in hard-to reach places with powerful oxi-action
• Use daily to clean retainers, full-plate dentures, partials and other dental appliances
• Reduces plaque buildup and removes food particles that can cause gum irritation
• The first dental cleanser tablet brand accepted by the American Dental Association
• Contains 1 pack of Efferdent Complete Clean Denture Cleanser, 126 tablets

Efferdent

• Overnight deep clean for brighter dentures
• 50% more brightening boosters (as compared to Efferdent Complete Clean)
• First and only denture cleanser tablet brand accepted by the American Dental Association
• Kills 99.9% of odor-causing bacteria
• Reduces plaque build-up and removes food particles that can cause gum irritation; 90 tablets

Efferdent

• KILLS 99.99% OF ODOR CAUSING BACTERIA: Our supreme anti-bacterial cleaning tablets are laboratory tested to kill 99% of the odor-causing bacteria in every corner of any oral appliance
• OPTIMAL RESULTS: M3 cleaning tablets are the most effective and safest solution on the market. Restore your appliance clarity through the removal of discoloration, stains, plaque, odors, and tartar
• ALL DENTAL APPLIANCES: Our tablets are perfect for dentures, retainers, aligners, invisalign, mouth guards, night guards, snore guards, sport, TMJ devices and all other removable dental appliances
• EASY TO USE: Just drop one tablet into warm tap water and soak your dental appliance for 10 minutes. Quickly restore any dental appliance in just minutes!
• PREMIUM QUALITY INGREDIENTS: M3 Naturals prides itself on sourcing every ingredient from the purest forms. We are committed to offering the highest-quality beauty products at an affordable price.

M3 Naturals

• ProTech Concentrated Denture Cleaner, in the convenient foil pack, is a remarkable, new prosthetic cleaner and stain remover that will revitalize old dentures; and will keep new dentures, partials and orthodontic appliances looking fresh and new.
• When used according to directions, ProTech will not harm the denture base, partial denture metal* or soft reline material.
• ProTech Cleaner is a non-chlorinated product, that will quickly and effectively clean and deodorize old and new partial and full dentures; to the delight of the patient, doctor and dental laboratory.
• Coffee, tea, tobacco, fruit and iron stains, along with tartar and plaque are removed safely and easily. It is also a fabulous calcium and calculus remover! Very few leading brands make this claim.

ProTech

• Suitable for retainers, dentures, mouth guards, Sport Guards and Night Guards. Helps remove stains, plaque and kills 99.99% of odor-causing bacteria.
• Made with a non-abrasive denture cleaner formula that cleans without scratching while helping to keep dental appliances clean and fresh.
• Polident 3 Minute Denture Cleanser kills 99.99 percent of odor causing bacteria in just 3 minutes (soaking only, in laboratory testing)
• Helps reduce plaque build up on your dentures (when used as directed)
• Denture tablets designed to dissolve quickly so the cleaning and freshening agents can get to work right away
• HSA and FSA eligible product

Polident

• Retainer Brite's anti-bacterial cleaning tablets keep your clear retainers, aligners, wire retainers, sports mouthguards, and nightguards clean and odor-free
• Intended for patients who use removable dental appliances - not for artificial teeth or partial dentures
• Easy to use and kills 99% of odor-causing bacteria, germs, plaque, and tartar that can remain on dental appliances
• Eliminate cloudy film and plaque buildup by soaking your dental appliances daily
• Package includes 96 individually wrapped tablets (3 month supply) to keep your appliances clear, bright, fresh, and free of buildup

Retainer Brite

• Compact ultrasonic cleaner uses sound waves to penetrate into crevices and cavities to remove particulates from dentures, retainers, and mouth guards
• Combined with iSonic White Denture Cleaning Powder
• Power button initiates a five-minute cleaning
• Compact size for tabletop use
• Operates on 100-120V;FREQ:42,000Hz

iSonic

• Professional Strength
• Kills 99.9% of odor causing bacteria
• Clean, Minty fresh breath
• For dentures and plastic partials
• Use daily to prevent plaque build-up

Regent

• Polident Overnight Whitening Denture Cleanser kills 99.99 percent of odor causing bacteria in just a quick overnight clean (soaking only, in laboratory testing)
• Helps reduce plaque buildup on your dentures (when used as directed)
• Denture cleaner that helps remove tough stains and whitens dentures
• Cleans denture material gently
• Polident is the number 1 dentist recommended brand of denture cleaner

Polident

• Pre-Measured Mint Flavored Foil Packet
• Safe, Convenient, Moisture Proof
• Removes Tough Coffee, Tea, Iron And Nicotine Stains
• Economy 22 Packet Box
• Each Packet Lasts Seven To Ten Days

Smile Again